Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8658566 | 0.79 | TSHR (0.35) | TSHRSOS1SOS2 | |
| SCHEMBL8658565 | 0.78 | SOS1 (0.31) | TSHRSOS1SOS2 | |
| SCHEMBL319587 | 0.78 | TSHR (0.34) | TSHRSOS1SOS2 | |
| SCHEMBL7484670 | 0.77 | — | — | |
| SCHEMBL7854611 | 0.77 | — | — | |
| Piperazine SCHEMBL28095267 | 0.76 | TSHR (0.33) | TSHRSOS1SOS2 | |
| SCHEMBL6838356 | 0.75 | TSHR (0.35) | TSHRSOS1SOS2 | |
| SCHEMBL30342849 | 0.74 | — | — | |
| SCHEMBL25263941 | 0.73 | TSHR (0.34) | TSHRSOS1SOS2 | |
| SCHEMBL477236 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5766505-A | MIXTURE OF POLYALKYLENE GLYCOL AND A GLYCOL ETHER | IDEMITSU KOSAN CO., LTD. (JP) | 1998-06-16 | — | — | US | disclosed |