SCHEMBL6838510

SCHEMBL6838510

Oc1ccccc1-c1nc2c(C(F)(F)F)nc3cc(Cl)ccc3c2n1CCC1CCNCC1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CASR P41180 5/20 0.42
NPY1R P25929 3/20 0.39
PIM1 P11309 3/20 0.36
CNR2 P34972 1/20 0.34
ACP1 P24666 1/20 0.34
CHRM1 P11229 4/20 0.34
CHRM3 P20309 2/20 0.34
CHEK2 O96017 1/20 0.33
PIM3 Q86V86 1/20 0.33
PIM2 Q9P1W9 1/20 0.33
ARF6 P62330 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM5 P08912 1/20 0.33
EIF4EBP1 Q13541 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6838393 0.91 CASR (0.37) CASRNPY1RCHEK2ARF6
SCHEMBL6837686 0.88 EGFR (0.41) NPY1RPIM1CNR2ACP1CHRM1
SCHEMBL6840065 0.88 MEN1 (0.42) CASRNPY1RPIM1ACP1EIF4EBP1
SCHEMBL6837773 0.86 NPY1R (0.38) NPY1RPIM1CNR2ACP1PIM3
SCHEMBL6838600 0.86 NPY1R (0.38) CASRNPY1RPIM1CNR2ACP1
SCHEMBL7500056 0.85 NPY1R (0.38) NPY1RPIM1CNR2ACP1PIM3
SCHEMBL6838050 0.83 HTR6 (0.38) NPY1RPIM1CNR2ACP1PIM3
SCHEMBL6837741 0.83 NPY1R (0.37) NPY1RPIM1CNR2ACP1PIM3
SCHEMBL6833773 0.82 NPY1R (0.37) NPY1RPIM1CNR2ACP1EIF4EBP1
SCHEMBL6837746 0.82 NPY1R (0.41) NPY1RPIM1CNR2ACP1CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040054182-A1 1h-imidazopyridine derivatives HOKURIKU SEIYAKU CO., LTD. (JP) 2004-03-18 US disclosed
EP-1256582-A1 1H-IMIDAZOPYRIDINE DERIVATIVES HOKURIKU SEIYAKU CO., LTD. (JP) 2002-11-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040054182-A1 1h-imidazopyridine derivatives IL2, IL1A, IL4 CASR 2571/4885NPY1R 1070/4885PIM1 261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.