Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R1 | P27986 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6838548 | 0.91 | SLC6A2 (0.32) | ALDH1A1KDM4EHPGDMAPTNPSR1 | |
| SCHEMBL6838620 | 0.91 | SLC6A2 (0.38) | ALDH1A1KDM4EHPGDSLC6A2SLC6A4 | |
| SCHEMBL6837812 | 0.89 | EGFR (0.39) | KDM4ELMNAHTTSLC6A2SLC6A4 | |
| SCHEMBL6837741 | 0.87 | NPY1R (0.37) | PIK3R1PIK3CAALDH1A1KDM4EHPGD | |
| SCHEMBL6838695 | 0.87 | SLC6A2 (0.32) | SLC6A2SLC6A4SLC6A3EPHA2 | |
| SCHEMBL6837670 | 0.85 | HTR6 (0.34) | ALDH1A1KDM4EHPGDHTTNPSR1 | |
| SCHEMBL6838090 | 0.84 | EPHA2 (0.34) | SLC6A2SLC6A4EPHA2MKNK1 | |
| SCHEMBL6837757 | 0.84 | SSTR4 (0.38) | ALDH1A1SLC6A2SLC6A4SLC6A3SMN1; SMN2 | |
| SCHEMBL6838194 | 0.83 | EPHA2 (0.32) | EPHA2MKNK1 | |
| SCHEMBL6838072 | 0.83 | HRH1 (0.35) | PIK3R1PIK3CAALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040054182-A1 | 1h-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2004-03-18 | — | — | US | disclosed |
| EP-1256582-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2002-11-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040054182-A1 | 1h-imidazopyridine derivatives | IL2, IL1A, IL4 | PIK3R1 2735/4885PIK3CA 3897/4885ALDH1A1 504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.