Glycerin

Glycerin

SCHEMBL6838628

CC(C)C1C=Cc2ccccc21.OCC(O)CO

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 0.37
HTR2A P28223 2/20 0.33
HTR6 P50406 1/20 0.33
KDM4E B2RXH2 3/20 0.32
CYP1A2 P05177 2/20 0.32
LMNA P02545 2/20 0.32
AGTR1 P30556 1/20 0.32
TRPA1 O75762 2/20 0.32
TP53 P04637 1/20 0.31
CHRM2 P08172 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CHRM1 P11229 1/20 0.31
DRD2 P14416 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
NFKB1 P19838 1/20 0.31
CHRM3 P20309 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2C P28335 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29658875 0.86 SIGMAR1 (0.41) SIGMAR1HTR2AHTR6KDM4ELMNA
SCHEMBL5597184 0.86 SIGMAR1 (0.41) SIGMAR1HTR2AHTR6KDM4ELMNA
SCHEMBL7656352 0.84 SIGMAR1 (0.40) SIGMAR1HTR2AHTR6KDM4ELMNA
SCHEMBL11129931 0.81 SIGMAR1 (0.37) SIGMAR1HTR2AHTR6KDM4ELMNA
Ethylene SCHEMBL10454556 0.81 SIGMAR1 (0.38) SIGMAR1HTR2AHTR6KDM4ELMNA
SCHEMBL6055183 0.81 SIGMAR1 (0.37) SIGMAR1HTR2AHTR6KDM4ELMNA
SCHEMBL27515506 0.80 HTR2A (0.37) SIGMAR1HTR2AHTR6KDM4ELMNA
Malonic Acid SCHEMBL11137101 0.79 SIGMAR1 (0.42) SIGMAR1HTR2AHTR6KDM4ECYP1A2
SCHEMBL6055178 0.76 SIGMAR1 (0.35) SIGMAR1HTR2AHTR6KDM4ELMNA
SCHEMBL29603716 0.75 SIGMAR1 (0.38) SIGMAR1HTR2AHTR6KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6822104-B2 SAPONIFICATION AND QUANTITATIVE ISOMERIZATION OF VEGETABLE OILS WITH A BASE POTASSIUM HYDROXIDE TO FORM A SOAP IN POLYETHYLENE GLYCOL, NEUTRALIZE WITH PHOSPHORIC ACID; BY-PRODUCT USE AS A FERTILIZER, NO COST FOR WASTE DISPOSAL HER MAJESTY THE QUEEN IN RIGHT OF CANADA, AS REPRESENTED BY THE MINISTER OF AGRICULTURE (CA) 2004-11-23 US disclosed
US-20040015001-A1 Method for commercial preparation of preffered isomeric forms of ester free conjugated fatty acids with solvents systems containing polyether alcohol solvents REANEY MARTIN J T (CA) 2004-01-22 US disclosed
WO-2001051597-A2 METHOD FOR COMMERCIAL PREPARATION OF PREFERRED ISOMERIC FORMS OF ESTER FREE CONJUGATED FATTY ACIDS IN POLYETHER ALCOHOL CONTAINING SOLVENTS HER MAJESTY IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF AGRICULTURE (CA) 2001-07-19 WO disclosed