Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CCL2 | P13500 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29658875 | 0.98 | SIGMAR1 (0.41) | SIGMAR1HTR2AHTR6KDM4EBRD4 | |
| SCHEMBL5597184 | 0.98 | SIGMAR1 (0.41) | SIGMAR1HTR2AHTR6KDM4EBRD4 | |
| Ethylene SCHEMBL10454556 | 0.92 | SIGMAR1 (0.38) | SIGMAR1HTR2AHTR6KDM4EBRD4 | |
| SCHEMBL6904952 | 0.88 | SIGMAR1 (0.37) | SIGMAR1HTR2AHTR6KDM4EBRD4 | |
| Hydrochloric Acid SCHEMBL7640182 | 0.86 | SIGMAR1 (0.36) | SIGMAR1HTR2AHTR6KDM4EBRD4 | |
| SCHEMBL28003595 | 0.85 | SIGMAR1 (0.38) | SIGMAR1HTR2AHTR6KDM4EBRD4 | |
| SCHEMBL668104 | 0.85 | SIGMAR1 (0.38) | SIGMAR1HTR2AHTR6KDM4EBRD4 | |
| SCHEMBL29603716 | 0.85 | SIGMAR1 (0.38) | SIGMAR1HTR2AHTR6KDM4EBRD4 | |
| Glycerin SCHEMBL6838628 | 0.84 | SIGMAR1 (0.37) | SIGMAR1HTR2AHTR6KDM4ELMNA | |
| SCHEMBL6684913 | 0.84 | SIGMAR1 (0.35) | SIGMAR1HTR2AHTR6KDM4EBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380334-B1 | ADDITION POLYMERIZATION OF OLEFINS WITH BRIDGED INDENYL TYPE METALLOCENE AND ACTIVATOR SUCH AS AN ALUMOXANE; HIGHER MELTING POINT POLYOLEFINS, SUCH AS POLYPROPYLENE | EXXONMOBIL CHEMICAL PATENTS INC. | 2002-04-30 | — | — | US | disclosed |
| US-6376411-B1 | COORDINATION POLYMERIZATION CATALYST ON SUPPORT | EXXONMOBIL CHEMICAL PATENTS INC. | 2002-04-23 | — | — | US | disclosed |