SCHEMBL6838795

SCHEMBL6838795

C[CH]c1ccccc1C(=O)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 3/20 0.55
GAA P10253 1/20 0.52
MAPT P10636 1/20 0.52
ALDH1A1 P00352 3/20 0.50
KMT2A Q03164 1/20 0.46
ELANE P08246 1/20 0.45
ATM Q13315 3/20 0.44
CDC25B P30305 1/20 0.44
TDP1 Q9NUW8 3/20 0.43
MAPK1 P28482 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
SRD5A2 P31213 1/20 0.43
HSP90AA1 P07900 1/20 0.43
PKM P14618 1/20 0.43
CCR6 P51684 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
TLR9 Q9NR96 1/20 0.43
POLB P06746 1/20 0.43
NR4A1 P22736 1/20 0.43
CYP2C8 P10632 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9497002 0.85 AKR1C3 (0.52) AKR1C3GAAMAPTALDH1A1KMT2A
SCHEMBL9496987 0.85 AKR1C3 (0.52) AKR1C3GAAMAPTALDH1A1KMT2A
SCHEMBL4459468 0.84 MAPT (0.53) AKR1C3GAAMAPTALDH1A1KMT2A
SCHEMBL1004343 0.82 AKR1C3 (0.57) AKR1C3GAAMAPTALDH1A1KMT2A
SCHEMBL2517175 0.81 ALDH1A1 (0.56) AKR1C3MAPTALDH1A1KMT2ATDP1
SCHEMBL8013503 0.81 AKR1C3 (0.52) AKR1C3GAAMAPTALDH1A1KMT2A
SCHEMBL7639009 0.80 AKR1C3 (0.55) AKR1C3GAAMAPTALDH1A1KMT2A
SCHEMBL173243 0.80 AKR1C3 (0.55) AKR1C3GAAMAPTALDH1A1KMT2A
SCHEMBL31727764 0.80 AKR1C3 (0.55) AKR1C3GAAMAPTALDH1A1KMT2A
SCHEMBL28475186 0.79 MAPT (0.47) AKR1C3GAAMAPTALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111225963-B Adhesive sheet for temporary fixation and method for manufacturing semiconductor device using the same 株式会社LG化学 2022-02-22 CN disclosed
CN-111225963-A Adhesive sheet for temporary fixation and method for manufacturing semiconductor device using the same 株式会社LG化学 2020-06-02 CN disclosed
US-6753410-B2 ANALYZING THE PROCESSING OF AMYLOID PROTEIN PRECURSOR (APP); ALZHEIMER'S DISEASE; ENZYME INHIBITORS OF GAMMA-SECRETASE, A PROTEASE, AND INHIBITS PROTEOLYSIS OF PRESENILIN-1 ON WHICH THE SECRETASE ACTIVITY IS DEPENDENT MERCK & CO., INC. 2004-06-22 US disclosed
US-20020013276-A1 Investigational compounds MERCK & CO., INC. 2002-01-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020013276-A1 Investigational compounds CBR1, CBR3, CNR1 AKR1C3 139/4885GAA 3511/4885MAPT 4625/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.