Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | ATM | Q13315 | 3/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1200734 | 0.87 | ALDH1A1 (0.40) | AKR1C3GAAMAPTALDH1A1CDC25B | |
| SCHEMBL1004343 | 0.82 | AKR1C3 (0.57) | AKR1C3GAAMAPTALDH1A1ATM | |
| SCHEMBL6835473 | 0.81 | ALDH1A1 (0.56) | AKR1C3MAPTALDH1A1TDP1PKM | |
| SCHEMBL173243 | 0.80 | AKR1C3 (0.55) | AKR1C3GAAMAPTALDH1A1ATM | |
| SCHEMBL31727764 | 0.80 | AKR1C3 (0.55) | AKR1C3GAAMAPTALDH1A1ATM | |
| SCHEMBL6838795 | 0.80 | AKR1C3 (0.55) | AKR1C3GAAMAPTALDH1A1ATM | |
| SCHEMBL8008684 | 0.78 | AKR1C3 (0.53) | AKR1C3GAAMAPTALDH1A1ATM | |
| SCHEMBL29263440 | 0.78 | AKR1C3 (0.53) | AKR1C3GAAMAPTALDH1A1ATM | |
| SCHEMBL29447165 | 0.78 | AKR1C3 (0.85) | AKR1C3GAAMAPTALDH1A1ATM | |
| SCHEMBL700595 | 0.78 | AKR1C3 (0.85) | AKR1C3GAAMAPTALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224195-A1 | C-ARYL GLUCOSIDE SGLT2 INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001027128-A1 | C-ARYL GLUCOSIDE SGLT2 INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-04-19 | — | — | WO | disclosed |
| EP-0005379-B1 | PHOTOSENSITIVE COMPOSITIONS CONTAINING CARBONYLIC HALIDES AS ACTIVATORS | Dynachem Corporation (US) | 1981-12-23 | — | — | EP | disclosed |