SCHEMBL6839591

SCHEMBL6839591

OC[C@@H]1C[C@H](O)[C@@H](O)C(O)O1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.33
CHRM5 P08912 2/20 0.33
CHRM1 P11229 2/20 0.33
CHRM3 P20309 2/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
ALDH1A1 P00352 2/20 0.32
LMNA P02545 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
SLC5A2 P31639 1/20 0.32
LGALS1 P09382 2/20 0.31
LGALS3 P17931 2/20 0.31
LGALS9 O00182 1/20 0.31
LGALS8 O00214 1/20 0.31
PYGL P06737 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14328427 1.00 TSHR (0.33) TSHRCHRM5CHRM1CHRM3CHRM2
SCHEMBL18850030 1.00 TSHR (0.33) TSHRCHRM5CHRM1CHRM3CHRM2
SCHEMBL6933813 1.00 TSHR (0.33) TSHRCHRM5CHRM1CHRM3CHRM2
SCHEMBL24520605 1.00 TSHR (0.33) TSHRCHRM5CHRM1CHRM3CHRM2
SCHEMBL12522349 1.00 TSHR (0.33) TSHRCHRM5CHRM1CHRM3CHRM2
SCHEMBL24943522 1.00 TSHR (0.33) TSHRCHRM5CHRM1CHRM3CHRM2
SCHEMBL6932362 1.00 TSHR (0.33) TSHRCHRM5CHRM1CHRM3CHRM2
SCHEMBL21370154 1.00 TSHR (0.33) TSHRCHRM5CHRM1CHRM3CHRM2
SCHEMBL22045699 1.00 TSHR (0.33) TSHRCHRM5CHRM1CHRM3CHRM2
SCHEMBL18349326 1.00 TSHR (0.33) TSHRCHRM5CHRM1CHRM3CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118291457-A Nucleic acid, composition containing nucleic acid, conjugate, preparation method and application 苏州瑞博生物技术股份有限公司 2024-07-05 CN claimed
CN-118291456-A Nucleic acid, composition containing nucleic acid, conjugate, preparation method and application 苏州瑞博生物技术股份有限公司 2024-07-05 CN claimed
CN-118256498-A Nucleic acid, pharmaceutical composition and conjugate, and preparation method and application thereof 苏州瑞博生物技术股份有限公司 2024-06-28 CN claimed
CN-118252843-A Nucleic acid, pharmaceutical composition and conjugate, and preparation method and application thereof 苏州瑞博生物技术股份有限公司 2024-06-28 CN claimed
CN-118217305-A Nucleic acid, pharmaceutical composition and conjugate, and preparation method and application thereof 苏州瑞博生物技术股份有限公司 2024-06-21 CN claimed
CN-118475356-A Drug conjugates of saccharide derivatives and their use as senescent cell lysing agents 鲁贝多生命科学公司 2024-08-09 CN disclosed
CN-113286888-B Nucleic acid, pharmaceutical composition and conjugate, and preparation method and application thereof 苏州瑞博生物技术股份有限公司 2023-12-22 CN disclosed
US-20230138729-A1 Coumarin Derivatives of Sugar Analogs and Uses Thereof Rubedo Life Sciences, Inc. 2023-05-04 US disclosed
US-20230138729-A1 Coumarin Derivatives of Sugar Analogs and Uses Thereof Rubedo Life Sciences, Inc. 2023-05-04 US disclosed
US-20230130134-A1 METHOD OF TREATING VIRAL INFECTIONS WITH HEXOSE TYPE MONOSACCHARIDES AND ANALOGS THEREOF BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-04-27 US disclosed
EP-4121060-A1 METHOD OF TREATING VIRAL INFECTIONS WITH HEXOSE TYPE MONOSACCHARIDES AND ANALOGS THEREOF Board of Regents, The University of Texas System (US) 2023-01-25 EP disclosed
CN-115515601-A Methods of treating viral infections with hexose-type monosaccharides and analogs thereof 得克萨斯大学体系董事会 2022-12-23 CN disclosed
WO-2012097052-A2 MONOSACCHARIDE-BASED COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE AND INFLAMMATORY DERMATOLOGICAL DISEASES INTERTECH BIO, LLC (US) 2012-07-19 WO disclosed
EP-2017281-A1 TOLL-LIKE RECEPTOR 9 AGONISTS Kyowa Hakko Kirin Co., Ltd. (JP) 2009-01-21 EP disclosed
US-20040024196-A1 Phase transfer catalyzed glycosidation of an indolocarbazole PETRILLO DANIEL E (US) 2004-02-05 US disclosed
EP-1333826-A2 PHASE TRANSFER CATALYZED GLYCOSIDATION OF AN INDOLOCARBAZOLE Merck & Co., Inc. (US) 2003-08-13 EP disclosed
US-6555677-B2 Preparing preferential compound; incubate sugar with activating agent, couple activated sugar with preferential compound, recover compound MERCK & CO., INC. 2003-04-29 US disclosed
US-20020058803-A1 Phase transfer catalyzed glycosidation of an indolocarbazole BANYU PHARMACEUTICAL CO., LTD. (JP) 2002-05-16 US disclosed
WO-2002036601-A2 PHASE TRANSFER CATALYZED GLYCOSIDATION OF AN INDOLOCARBAZOLE MERCK & CO., INC. (US) 2002-05-10 WO disclosed
WO-1993017032-A1 TECHNIQUES AND INTERMEDIATES FOR PREPARING NON-PEPTIDE PEPTIDOMIMETICS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1993-09-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040024196-A1 Phase transfer catalyzed glycosidation of an indolocarbazole UGGT1, UGCG, GPI TSHR 2347/4885CHRM5 4775/4885CHRM1 4732/4885
US-20230138729-A1 Coumarin Derivatives of Sugar Analogs and Uses Thereof GLA, ENGASE, GLB1 TSHR 3564/4885CHRM5 2889/4885CHRM1 2523/4885
US-20020058803-A1 Phase transfer catalyzed glycosidation of an indolocarbazole UGGT1, UGCG, GPI TSHR 2347/4885CHRM5 4775/4885CHRM1 4732/4885
US-20230130134-A1 METHOD OF TREATING VIRAL INFECTIONS WITH HEXOSE TYPE MONOSACCHARIDES AND ANALOGS THEREOF G6PD, FBP1, ALDOA TSHR 3732/4885CHRM5 4276/4885CHRM1 4401/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.