Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.34 |
| ▸ | CHRNG | P07510 | 1/20 | 0.34 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CHRND | Q07001 | 1/20 | 0.34 |
| ▸ | CHRNA2 | Q15822 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6839637 | 1.00 | SLC6A3 (0.36) | SLC6A3SLC6A4HSP90AA1HSP90AB1KCNH2 | |
| SCHEMBL6846186 | 0.84 | HPGD (0.37) | SLC6A3SLC6A4HSP90AA1HSP90AB1HPGD | |
| SCHEMBL6846185 | 0.84 | HPGD (0.37) | SLC6A3SLC6A4HSP90AA1HSP90AB1HPGD | |
| SCHEMBL5870737 | 0.69 | PRMT5 (0.43) | SLC6A3SLC6A4KCNH2 | |
| SCHEMBL7328555 | 0.66 | KDM4E (0.46) | SLC6A3SLC6A4KCNH2ALDH1A1HPGD | |
| SCHEMBL5870697 | 0.66 | SLC6A2 (0.40) | SLC6A3SLC6A4KCNH2 | |
| SCHEMBL13227345 | 0.64 | SLC6A3 (0.61) | SLC6A3SLC6A4CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL4433623 | 0.64 | SLC6A3 (0.61) | SLC6A3SLC6A4CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL12313096 | 0.64 | SLC6A3 (0.61) | SLC6A3SLC6A4CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL3587139 | 0.64 | SLC6A3 (0.61) | SLC6A3SLC6A4CHRNB2CHRNA4CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040235906-A1 | Substituted amine derivatives and their use as monoamine neurotransmitter re-up-take inhibitors | NEUROSEARCH A/S (DK) | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235906-A1 | Substituted amine derivatives and their use as monoamine neurotransmitter re-up-take inhibitors | SLC6A2, SLC18A2, MAOB | SLC6A3 5/4885SLC6A4 6/4885HSP90AA1 4335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.