Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7327904 | 0.92 | KDM4E (0.51) | KDM4EHCRTR1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL4321291 | 0.79 | KDM4E (0.48) | KDM4EHCRTR1HPGDALDH1A1SLC6A4 | |
| Hydrochloric Acid SCHEMBL4156097 | 0.78 | KDM4E (0.47) | KDM4EHCRTR1HPGDALDH1A1SLC6A4 | |
| SCHEMBL7321450 | 0.78 | KDM4E (0.53) | KDM4EHCRTR1ALDH1A1SLC6A4SLC6A2 | |
| SCHEMBL2240729 | 0.74 | SLC6A4 (0.68) | SLC6A4SLC6A2SLC6A3 | |
| Oxalic Acid SCHEMBL7331859 | 0.72 | KDM4E (0.56) | KDM4EHCRTR1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7358151 | 0.71 | KDM4E (0.46) | KDM4EHCRTR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5870737 | 0.71 | PRMT5 (0.43) | SLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL7236230 | 0.70 | KDM4E (0.56) | KDM4EALDH1A1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6608189 | 0.70 | LTA4H (0.49) | KDM4EHCRTR1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629190-A1 | COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-12-21 | — | — | EP | claimed |
| WO-1993015052-A1 | COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-08-05 | — | — | WO | claimed |