Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 11/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6840558 | 0.91 | F10 (0.58) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL6839798 | 0.89 | RAB9A (0.54) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL6839857 | 0.88 | RAB9A (0.55) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| Acetic Acid SCHEMBL6839721 | 0.88 | F10 (0.57) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL6839785 | 0.82 | RAB9A (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL6839693 | 0.78 | SMN1; SMN2 (0.50) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL5166228 | 0.77 | F10 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL5164360 | 0.77 | F10 (0.59) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL4394945 | 0.76 | ALDH1A1 (0.62) | NPC1RAB9ASMN1; SMN2ALDH1A1F10 | |
| SCHEMBL5164502 | 0.75 | F10 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082563-A1 | Phenyl derivatives 3 | MERCK PATENT GMBH (DE) | 2004-04-29 | — | — | US | claimed |
| US-20040082563-A1 | Phenyl derivatives 3 | MERCK PATENT GMBH (DE) | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082563-A1 | Phenyl derivatives 3 | F2, F11, F12 | NPC1 2264/4885RAB9A 1592/4885SMN1; SMN2 3408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.