Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | CES2 | O00748 | 4/20 | 0.54 |
| ▸ | CES1 | P23141 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10710889 | 1.00 | GAA (0.63) | GAACYP2C19CES2CES1NPC1 | |
| SCHEMBL6839865 | 1.00 | GAA (0.63) | GAACYP2C19CES2CES1NPC1 | |
| SCHEMBL5360093 | 0.81 | GAA (0.68) | GAACYP2C19CES2CES1NPC1 | |
| SCHEMBL11461735 | 0.81 | GAA (0.68) | GAACYP2C19CES2CES1NPC1 | |
| SCHEMBL4454729 | 0.81 | GAA (0.68) | GAACYP2C19CES2CES1NPC1 | |
| SCHEMBL11032602 | 0.80 | HSD17B1 (0.48) | GAACYP2C19CES2SMN1; SMN2ALDH1A1 | |
| SCHEMBL11491554 | 0.80 | ALDH1A1 (0.50) | GAACYP2C19CES2CES1NPC1 | |
| SCHEMBL11491555 | 0.80 | ALDH1A1 (0.50) | GAACYP2C19CES2CES1NPC1 | |
| SCHEMBL8532484 | 0.80 | CES2 (0.52) | GAACYP2C19CES2CES1NPC1 | |
| SCHEMBL12131284 | 0.80 | GAA (0.65) | GAACYP2C19CES2CES1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111244547-B | Electrolyte containing aromatic oxime additive and preparation method and application thereof | 四川虹微技术有限公司 | 2021-09-17 | — | — | CN | disclosed |
| US-11077107-B2 | Triazolopyrazine | BOEHRINGER INGELHEIM INTERNATIONAL GMBH | 2021-08-03 | — | — | US | disclosed |
| CN-111244547-A | Electrolyte containing aromatic oxime additive and preparation method and application thereof | 四川虹微技术有限公司 | 2020-06-05 | — | — | CN | disclosed |
| US-20190240219-A1 | TRIAZOLOPYRAZINE | BOEHRINGER INGELHEIM INT (DE) | 2019-08-08 | — | — | US | disclosed |
| US-10328074-B2 | Substituted [1,2,4]triazolo[4,3-a]pyrazines as BRD4 inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-06-25 | — | — | US | disclosed |
| EP-2925761-B1 | TRIAZOLOPYRAZINES AS BRD4 INHIBITORS FOR USE IN THE TREATMENT OF CANCER | BOEHRINGER INGELHEIM INT (DE) | 2017-07-05 | — | — | EP | disclosed |
| US-20160129001-A1 | SUBSTITUTED [1,2,4]TRIAZOLO[4,3-a]PYRAZINES AS BRD4 INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2016-05-12 | — | — | US | disclosed |
| US-9266891-B2 | Substituted [1,2,4]triazolo[4,3-A]pyrazines that are BRD4 inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-02-23 | — | — | US | disclosed |
| EP-2925761-A1 | TRIAZOLOPYRAZINE | Boehringer Ingelheim International GmbH (DE) | 2015-10-07 | — | — | EP | disclosed |
| WO-2014076237-A1 | TRIAZOLOPYRAZINE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-05-22 | — | — | WO | disclosed |
| EP-0146505-B1 | IMAGE FORMATION PROCESS | CIBA-GEIGY AG (CH) | 1990-04-04 | — | — | EP | disclosed |
| US-4721734-A | PHOTOPOLYMERIZATION OF UNSATURATED COMPOUNDS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-01-26 | — | — | US | disclosed |
| EP-0151372-A2 | Image production | CIBA-GEIGY AG (CH) | 1985-08-14 | — | — | EP | disclosed |
| EP-0146505-A2 | Image formation process | CIBA-GEIGY AG (CH) | 1985-06-26 | — | — | EP | disclosed |
| US-4477681-A | PHOTOPOLYMERIZATION AND HARDENING OF PRINTING DYES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-10-16 | — | — | US | disclosed |
| US-4347111-A | PHOTOPOLYMERIZATION OF UNSATURATED COMPOUNDS, HARDENING OF PRINTING DYES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-08-31 | — | — | US | disclosed |
| US-4330643-A | Process for production of acryloyloxy- or methacryloyloxy-terminated polyesters | TOAGOSEI CHEMICAL INDUSTRY CO., LTD. (JP) | 1982-05-18 | — | — | US | disclosed |
| US-4229579-A | OPTICAL BRIGHTENERS | BAYER AKTIENGESELLSCHAFT (DE) | 1980-10-21 | — | — | US | disclosed |
| US-4144243-A | OPTICAL BRIGHTENERS FOR TEXTILES AND LACQUEARS | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-13 | — | — | US | disclosed |
| US-4005098-A | BRIGHTENING AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190240219-A1 | TRIAZOLOPYRAZINE | MKI67, CCNI, CCNT2 | GAA 1460/4885CYP2C19 533/4885CES2 1283/4885 |
| US-20160129001-A1 | SUBSTITUTED [1,2,4]TRIAZOLO[4,3-a]PYRAZINES AS BRD4 INHIBITORS | BRD4, BRD3, BICRA | GAA 4822/4885CYP2C19 3493/4885CES2 4048/4885 |
| US-10328074-B2 | Substituted [1,2,4]triazolo[4,3-a]pyrazines as BRD4 inhibitors | BRD4, BRD3, BICRA | GAA 4822/4885CYP2C19 3493/4885CES2 4048/4885 |
| US-11077107-B2 | Triazolopyrazine | MKI67, CCNI, CCNT2 | GAA 1460/4885CYP2C19 533/4885CES2 1283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.