Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA8 | P11142 | 3/20 | 0.60 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.60 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.57 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HBB | P68871 | 1/20 | 0.57 |
| ▸ | GAPDH | P04406 | 2/20 | 0.55 |
| ▸ | CDK1 | P06493 | 2/20 | 0.55 |
| ▸ | CDK2 | P24941 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.55 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.55 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.55 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.55 |
| ▸ | DPP4 | P27487 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.55 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6838655 | 0.82 | HSPA8 (0.71) | HSPA8HSPA5SMN1; SMN2LMNATP53 | |
| SCHEMBL1740449 | 0.82 | HSPA5 (0.63) | HSPA8HSPA5CDK5CDK5R1SMN1; SMN2 | |
| SCHEMBL6380760 | 0.80 | HSPA8 (0.61) | HSPA8HSPA5CDK5CDK5R1SMN1; SMN2 | |
| SCHEMBL20419157 | 0.80 | HSPA5 (0.61) | HSPA8HSPA5CDK5CDK5R1SMN1; SMN2 | |
| Tubercidin SCHEMBL23351430 | 0.80 | ADK (0.82) | SMN1; SMN2GAPDHDOT1LDPP4MEN1 | |
| Tubercidin SCHEMBL20419149 | 0.80 | ADK (0.82) | SMN1; SMN2GAPDHDOT1LDPP4MEN1 | |
| Tubercidin SCHEMBL11239877 | 0.80 | ADK (0.82) | SMN1; SMN2GAPDHDOT1LDPP4MEN1 | |
| Tubercidin SCHEMBL23982115 | 0.80 | ADK (0.82) | SMN1; SMN2GAPDHDOT1LDPP4MEN1 | |
| Tubercidin SCHEMBL20938187 | 0.80 | ADK (0.82) | SMN1; SMN2GAPDHDOT1LDPP4MEN1 | |
| Tubercidin SCHEMBL8259 | 0.80 | ADK (0.82) | SMN1; SMN2GAPDHDOT1LDPP4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063658-A1 | Nucleoside derivatives for treating hepatitis C virus infection | GENELABS TECHNOLOGIES, INC. | 2004-04-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063658-A1 | Nucleoside derivatives for treating hepatitis C virus infection | HAVCR2, PNP, NTPCR | HSPA8 1928/4885HSPA5 2092/4885CDK5 888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.