Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 2/20 | 0.61 |
| ▸ | HSPA8 | P11142 | 2/20 | 0.61 |
| ▸ | CDK1 | P06493 | 2/20 | 0.59 |
| ▸ | CDK2 | P24941 | 2/20 | 0.59 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.59 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.59 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.59 |
| ▸ | ADK | P55263 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | GAPDH | P04406 | 2/20 | 0.56 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.56 |
| ▸ | DPP4 | P27487 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.56 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.56 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1740449 | 0.88 | HSPA5 (0.63) | HSPA5HSPA8CDK1CDK2CCNB1 | |
| SCHEMBL6380760 | 0.86 | HSPA8 (0.61) | HSPA5HSPA8CDK1CDK2CCNB1 | |
| SCHEMBL20419330 | 0.83 | HSPA8 (0.58) | HSPA5HSPA8CDK1CDK2CCNB1 | |
| SCHEMBL20419169 | 0.83 | HSPA8 (0.58) | HSPA5HSPA8CDK1CDK2CCNB1 | |
| SCHEMBL17918401 | 0.81 | HSPA8 (0.55) | HSPA5HSPA8CDK1CDK2CCNB1 | |
| SCHEMBL6840004 | 0.80 | HSPA8 (0.60) | HSPA5HSPA8CDK1CDK2CCNB1 | |
| SCHEMBL20917327 | 0.79 | RAPGEF3 (0.49) | HSPA5HSPA8CDK1CDK2CCNB1 | |
| SCHEMBL20419191 | 0.79 | RAPGEF3 (0.49) | HSPA5HSPA8CDK1CDK2CCNB1 | |
| SCHEMBL20419165 | 0.79 | RAPGEF3 (0.49) | HSPA5HSPA8CDK1CDK2CCNB1 | |
| SCHEMBL12030991 | 0.79 | NADK (0.79) | HSPA5HSPA8SMN1; SMN2GAPDHDOT1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210338706-A1 | ADENOSINE ANALOG AND ITS USE IN REGULATING THE CIRCADIAN CLOCK | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-11-04 | — | — | US | disclosed |
| WO-2018133854-A1 | ADENOSINE ANALOG AND ITS USE IN REGULATING THE CIRCADIAN CLOCK | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2018-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210338706-A1 | ADENOSINE ANALOG AND ITS USE IN REGULATING THE CIRCADIAN CLOCK | PER2, CRY1, ADORA2A | HSPA5 4535/4885HSPA8 4447/4885CDK1 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.