Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | QPCT | Q16769 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ANTXR2 | P58335 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6840673 | 0.84 | PTGS1 (0.43) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL6344640 | 0.69 | AKR1C3 (0.47) | EGFRRETKDRADORA3QPCT | |
| SCHEMBL5540550 | 0.66 | CYP1A2 (0.45) | ALDH1A1MAPTKDM4ENPC1CA12 | |
| SCHEMBL6348904 | 0.65 | EGFR (0.42) | EGFRRETKDRADORA3QPCT | |
| SCHEMBL533344 | 0.63 | CA12 (0.53) | ALDH1A1KDM4ENPC1RAB9ACA12 | |
| SCHEMBL2493501 | 0.62 | LTA4H (0.52) | ALDH1A1MAPTSLC5A1SLC5A2CA12 | |
| SCHEMBL70827 | 0.62 | LTA4H (0.52) | ALDH1A1MAPTSLC5A1SLC5A2CA12 | |
| SCHEMBL28069517 | 0.61 | ADORA3 (0.55) | EGFRRETKDRADORA3QPCT | |
| SCHEMBL29196803 | 0.61 | SLC5A1 (0.50) | ALDH1A1MAPTMAPK1KDM4ENPC1 | |
| SCHEMBL971905 | 0.60 | LTA4H (0.45) | ADORA3ALDH1A1MAPTKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040024015-A1 | Tumor radiosensitization and /or chemopotentiation using isocoumarin derivatives | GLBC LLC | 2004-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040024015-A1 | Tumor radiosensitization and /or chemopotentiation using isocoumarin derivatives | HCCS, IDH2, IDH3A | EGFR 3349/4885RET 3626/4885KDR 4331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.