SCHEMBL70827

SCHEMBL70827

CCOc1cc(O)cc(O)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.52
NQO1 P15559 1/20 0.50
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45
CA14 Q9ULX7 1/20 0.45
SLC5A1 P13866 2/20 0.42
SLC5A2 P31639 2/20 0.42
BACE1 P56817 1/20 0.42
ADRA2A P08913 2/20 0.42
GPR84 Q9NQS5 1/20 0.41
CALM1 P0DP23 1/20 0.41
TSHR P16473 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
ALDH1A1 P00352 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2493501 0.95 LTA4H (0.52) LTA4HNQO1CA12CA1CA2
SCHEMBL9774077 0.86 ALDH1A1 (0.50) LTA4HNQO1CA12CA1CA2
SCHEMBL9278662 0.86 CALM1 (0.51) LTA4HNQO1CA1CA2BACE1
SCHEMBL2395245 0.84 CA12 (0.48) LTA4HNQO1CA12CA1CA9
SCHEMBL200566 0.84 CHRNB4 (0.49) LTA4HNQO1SLC5A1SLC5A2ADRA2A
SCHEMBL13384702 0.84 LTA4H (0.44) LTA4HNQO1SLC5A1SLC5A2TSHR
SCHEMBL8048694 0.84 LTA4H (0.48) LTA4HNQO1CA12CA1CA2
SCHEMBL3574765 0.83 ACHE (0.54) LTA4HNQO1SLC5A1SLC5A2GPR84
SCHEMBL13085659 0.81 MAPT (0.43) LTA4HNQO1SLC5A1SLC5A2GPR84
SCHEMBL1621388 0.81 ALDH1A1 (0.50) LTA4HSLC5A1SLC5A2BACE1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4112003-A Process for preparing polyphenols GIVAUDAN CORPORATION (US) 1978-09-05 US claimed
EP-3134421-B1 NEW LIPOPHENOL COMPOUNDS AND USES THEREOF INST NAT SANTE RECH MED (FR) 2022-04-20 EP disclosed
US-11129781-B2 Agent for hair deforming treatment KAO CORPORATION (JP) 2021-09-28 US disclosed
US-11045402-B2 Hair cosmetic composition KAO CORPORATION (JP) 2021-06-29 US disclosed
US-10959925-B2 Hair cosmetic composition KAO CORPORATION (JP) 2021-03-30 US disclosed
EP-3228302-B1 HAIR DEFORMATION TREATMENT AGENT KAO CORP (JP) 2020-09-02 EP disclosed
CN-106999382-B Hair deforming agent 花王株式会社 2020-07-10 CN disclosed
CN-106999380-B Hair deforming agent 花王株式会社 2020-05-05 CN disclosed
US-20190290564-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2019-09-26 US disclosed
US-20190254943-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2019-08-22 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-8030347-B2 Cylopenta[b]benzofuran derivatives and the utilization thereof BAYER HEALTHCARE AG (DE) 2011-10-04 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-20090018113-A1 Novel Cylopenta[B]Benzofuran Derivatives and the Utilization Thereof BAYER HEALTHCARE AG (DE) 2009-01-15 US disclosed
EP-1751127-A2 NOVEL CYLOPENTA¬B|BENZOFURAN DERIVATIVES AND THE UTILIZATION THEREOF Bayer HealthCare AG (DE) 2007-02-14 EP disclosed
WO-2005113529-A2 NOVEL CYLOPENTA[B]BENZOFURAN DERIVATIVES AND THE UTILIZATION THEREOF BAYER HEALTHCARE AG (DE) 2005-12-01 WO disclosed
EP-0065720-B1 PROCESS FOR PREPARING HYDROXYPHENYL AMINE DERIVATIVES CASSELLA Aktiengesellschaft (DE) 1985-01-09 EP disclosed
EP-0065720-A1 Process for preparing hydroxyphenyl amine derivatives CASSELLA Aktiengesellschaft (DE) 1982-12-01 EP disclosed
US-4112003-A Process for preparing polyphenols GIVAUDAN CORPORATION (US) 1978-09-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 LTA4H 813/4885NQO1 3710/4885CA12 1221/4885
US-11045402-B2 Hair cosmetic composition CUTA, GRHPR, POLR1C LTA4H 2150/4885NQO1 1363/4885CA12 720/4885
US-10959925-B2 Hair cosmetic composition CUTA, POLR1C, GRHPR LTA4H 3271/4885NQO1 817/4885CA12 567/4885
US-20190254943-A1 HAIR COSMETIC COMPOSITION CUTA, POLR1C, GRHPR LTA4H 3271/4885NQO1 817/4885CA12 567/4885
US-20090018113-A1 Novel Cylopenta[B]Benzofuran Derivatives and the Utilization Thereof FKBP1A, FKBP2, FKBP1B LTA4H 1308/4885NQO1 803/4885CA12 3665/4885
US-11129781-B2 Agent for hair deforming treatment GRHPR, SLC26A4, COL1A1 LTA4H 3057/4885NQO1 1270/4885CA12 1628/4885
US-20190290564-A1 HAIR COSMETIC COMPOSITION GRHPR, POLR1C, TYR LTA4H 2755/4885NQO1 426/4885CA12 745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.