Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6841385 | 0.91 | ALDH1A1 (0.35) | ALDH1A1KDM4EASGR1TSHRSMN1; SMN2 | |
| SCHEMBL6841531 | 0.91 | ALDH1A1 (0.35) | ALDH1A1KDM4EASGR1TSHRSMN1; SMN2 | |
| SCHEMBL6836198 | 0.84 | NFKB1 (0.39) | ALDH1A1HPGDKDM4ELMNASMN1; SMN2 | |
| SCHEMBL6836199 | 0.84 | NFKB1 (0.39) | ALDH1A1HPGDKDM4ELMNASMN1; SMN2 | |
| SCHEMBL14475704 | 0.84 | NFKB1 (0.43) | ALDH1A1HPGDRECQLMAPK1L3MBTL1 | |
| SCHEMBL14475702 | 0.80 | ALDH1A1 (0.44) | ALDH1A1HPGDRECQLMAPK1L3MBTL1 | |
| SCHEMBL7862552 | 0.80 | HPGD (0.39) | ALDH1A1HPGDRECQLMAPK1ASGR1 | |
| SCHEMBL6818575 | 0.80 | HPGD (0.39) | ALDH1A1HPGDRECQLMAPK1ASGR1 | |
| SCHEMBL6841691 | 0.79 | CYP1A2 (0.35) | ALDH1A1KDM4ETSHRCYP1A2CYP2C19 | |
| SCHEMBL8893825 | 0.79 | CYP1A2 (0.35) | ALDH1A1KDM4ETSHRCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040167351-A1 | Method for preparing (1R,4S)-2-azabicyclo[2.2.1]hept-5-ene-3-one derivatives | BERNEGGER-EGLI CHRISTINE (CH) | 2004-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040167351-A1 | Method for preparing (1R,4S)-2-azabicyclo[2.2.1]hept-5-ene-3-one derivatives | APEH, CYP51A1, CYP8B1 | ALDH1A1 212/4885HPGD 273/4885RECQL 1458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.