Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 3/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NAE1 | Q13564 | 1/20 | 0.30 |
| ▸ | UBA3 | Q8TBC4 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893825 | 1.00 | CYP1A2 (0.35) | CYP1A2CYP2C19HSD17B10MMP2ANPEP | |
| SCHEMBL10357493 | 1.00 | CYP1A2 (0.35) | CYP1A2CYP2C19HSD17B10MMP2ANPEP | |
| SCHEMBL6836198 | 0.84 | NFKB1 (0.39) | HSD17B10SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL6836199 | 0.84 | NFKB1 (0.39) | HSD17B10SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL6917661 | 0.84 | NFKB1 (0.39) | HSD17B10SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL6841531 | 0.82 | ALDH1A1 (0.35) | SMN1; SMN2NPSR1TSHRKDM4EALDH1A1 | |
| SCHEMBL6841385 | 0.82 | ALDH1A1 (0.35) | SMN1; SMN2NPSR1TSHRKDM4EALDH1A1 | |
| SCHEMBL14199306 | 0.81 | CHRNB2 (0.33) | CYP1A2HSD17B10MMP2ANPEPCHRNB2 | |
| SCHEMBL25600138 | 0.81 | CHRNB2 (0.33) | CYP1A2HSD17B10MMP2ANPEPCHRNB2 | |
| SCHEMBL6840860 | 0.81 | SMN1; SMN2 (0.37) | SMN1; SMN2NPSR1ATMKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040167351-A1 | Method for preparing (1R,4S)-2-azabicyclo[2.2.1]hept-5-ene-3-one derivatives | BERNEGGER-EGLI CHRISTINE (CH) | 2004-08-26 | — | — | US | disclosed |
| EP-0349242-B1 | Therapeutic nucleosides | WELLCOME FOUND (GB) | 1995-03-22 | — | — | EP | disclosed |
| EP-0424064-B1 | Chiral azabicyloheptanone and a process for their preparation | CHIROSCIENCE LTD (GB) | 1995-02-08 | — | — | EP | disclosed |
| EP-0393499-A1 | Process for preparing carbovir and new intermediate products therefor | F. HOFFMANN-LA ROCHE AG (CH) | 1990-10-24 | — | — | EP | disclosed |
| US-4939252-A | Novel intermediates for the preparation of Carbovir | HOFFMANN-LA ROCHE INC. (US) | 1990-07-03 | — | — | US | disclosed |
| EP-0349242-A2 | Therapeutic nucleosides | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-01-03 | — | — | EP | disclosed |
| US-4383114-A | ANTITUMOR AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1983-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040167351-A1 | Method for preparing (1R,4S)-2-azabicyclo[2.2.1]hept-5-ene-3-one derivatives | APEH, CYP51A1, CYP8B1 | CYP1A2 26/4885CYP2C19 195/4885HSD17B10 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.