Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | TGM2 | P21980 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15739517 | 1.00 | LMNA (0.61) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL21338346 | 0.93 | LMNA (0.55) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL11990340 | 0.87 | SMN1; SMN2 (0.73) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL698335 | 0.87 | LMNA (0.60) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL19416263 | 0.87 | LMNA (0.60) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL12895393 | 0.86 | LMNA (0.58) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL13531477 | 0.86 | SMN1; SMN2 (0.71) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL16389741 | 0.85 | TGM2 (0.54) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL23871966 | 0.85 | LMNA (0.61) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL7159271 | 0.85 | HTT (0.62) | LMNASMN1; SMN2HTTTGM2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759509-B1 | CONJUGATES CONTAINING A TARGETING LIGAND, SUCH AS AN ANTIBODY, A THERAPEUTICALLY ACTIVE DRUG AND A BRANCHED PEPTIDE LINKER | BRISTOL-MYERS SQUIBB COMPANY | 2004-07-06 | — | — | US | disclosed |