Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.51 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19416263 | 1.00 | LMNA (0.60) | LMNASMN1; SMN2HTTTGM2SLC1A3 | |
| SCHEMBL12355769 | 0.92 | HTT (0.53) | LMNASMN1; SMN2HTTTGM2SLC1A3 | |
| SCHEMBL12355770 | 0.91 | HTT (0.52) | LMNASMN1; SMN2HTTTGM2SLC1A3 | |
| SCHEMBL11990353 | 0.88 | LMNA (0.64) | LMNASMN1; SMN2HTTTGM2SLC1A3 | |
| SCHEMBL15739517 | 0.87 | LMNA (0.61) | LMNASMN1; SMN2HTTTGM2SLC1A3 | |
| SCHEMBL6840808 | 0.87 | LMNA (0.61) | LMNASMN1; SMN2HTTTGM2SLC1A3 | |
| SCHEMBL16789587 | 0.86 | HTT (0.62) | LMNASMN1; SMN2HTTTGM2SLC1A3 | |
| SCHEMBL16541571 | 0.86 | LMNA (0.57) | LMNASMN1; SMN2HTTTGM2SLC1A3 | |
| SCHEMBL11990340 | 0.86 | SMN1; SMN2 (0.73) | LMNASMN1; SMN2HTTTGM2SLC1A3 | |
| SCHEMBL614872 | 0.85 | LMNA (0.71) | LMNASMN1; SMN2HTTTGM2SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051968-B1 | LUMINESCENT MACROCYCLIC LANTHANIDE COMPLEXES | UNIV CALIFORNIA (US) | 2020-04-29 | — | — | EP | disclosed |
| EP-2423201-B1 | Luminescent macrocyclic lanthanide complexes | UNIV CALIFORNIA (US) | 2017-10-04 | — | — | EP | disclosed |
| US-9439984-B2 | Macrocycles | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-09-13 | — | — | US | disclosed |
| US-20150157746-A1 | MACROCYCLES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-06-11 | — | — | US | disclosed |
| US-8729258-B2 | Luminescent macrocyclic lanthanide complexes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-05-20 | — | — | US | disclosed |
| WO-2013187971-A2 | MACROCYCLES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-12-19 | — | — | WO | disclosed |
| US-20120329174-A1 | LUMINESCENT MACROCYCLIC LANTHANIDE COMPLEXES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-12-27 | — | — | US | disclosed |
| US-8173800-B2 | Hydroxy-isophthalamide moieties; antibodies; high stability, luminescence; kits | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-05-08 | — | — | US | disclosed |
| EP-2423201-A1 | Luminescent macrocyclic lanthanide complexes | The Regents of The University of California (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-2051968-A2 | LUMINESCENT MACROCYCLIC LANTHANIDE COMPLEXES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-04-29 | — | — | EP | disclosed |
| US-20080213917-A1 | LUMINESCENT MACROCYCLIC LANTHANIDE COMPLEXES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-09-04 | — | — | US | disclosed |
| WO-2008063721-A2 | LUMINESCENT MACROCYCLIC LANTHANIDE COMPLEXES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080213917-A1 | LUMINESCENT MACROCYCLIC LANTHANIDE COMPLEXES | SSB, HACD3, CLTA | LMNA 2003/4885SMN1; SMN2 4141/4885HTT 281/4885 |
| US-20120329174-A1 | LUMINESCENT MACROCYCLIC LANTHANIDE COMPLEXES | SSB, HACD3, CLTA | LMNA 2003/4885SMN1; SMN2 4141/4885HTT 281/4885 |
| US-20150157746-A1 | MACROCYCLES | SLC39A14, SLC39A3, SLC40A1 | LMNA 3805/4885SMN1; SMN2 3483/4885HTT 390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.