Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.81 |
| ▸ | MEN1 | O00255 | 3/20 | 0.81 |
| ▸ | POLB | P06746 | 2/20 | 0.81 |
| ▸ | LMNA | P02545 | 2/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.81 |
| ▸ | PKM | P14618 | 1/20 | 0.81 |
| ▸ | APEX1 | P27695 | 1/20 | 0.81 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.79 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | NT5E | P21589 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL678618 | 1.00 | KMT2A (0.81) | KMT2AMEN1POLBLMNATDP1 | |
| SCHEMBL9681496 | 0.90 | POLB (1.00) | KMT2AMEN1POLBLMNATDP1 | |
| SCHEMBL1353478 | 0.90 | POLB (1.00) | KMT2AMEN1POLBLMNATDP1 | |
| SCHEMBL137276 | 0.90 | POLB (1.00) | KMT2AMEN1POLBLMNATDP1 | |
| SCHEMBL2128727 | 0.90 | POLB (1.00) | KMT2AMEN1POLBLMNATDP1 | |
| SCHEMBL30319980 | 0.90 | POLB (1.00) | KMT2AMEN1POLBLMNATDP1 | |
| SCHEMBL9767723 | 0.90 | NPC1 (0.76) | KMT2AMEN1POLBLMNATDP1 | |
| SCHEMBL10939703 | 0.90 | NPC1 (0.76) | KMT2AMEN1POLBLMNATDP1 | |
| SCHEMBL611657 | 0.90 | NPC1 (0.76) | KMT2AMEN1POLBLMNATDP1 | |
| SCHEMBL8442129 | 0.88 | POLB (0.96) | KMT2AMEN1POLBLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7635662-B2 | Compound for color-producing composition, and recording material | CHEMIPRO KASEI KAISHA, LTD. (JP) | 2009-12-22 | — | — | US | claimed |
| EP-3568390-B1 | SMALL MOLECULE ACTIVATORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) AND USES THEREOF | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INST (US) | 2024-03-06 | — | — | EP | disclosed |
| US-11806337-B2 | Small molecule activators of nicotinamide phosphoribosyltransferase (NAMPT) and uses thereof | Sanford Burnham Prebys Medical Discovery Institute (US) | 2023-11-07 | — | — | US | disclosed |
| US-11806337-B2 | Small molecule activators of nicotinamide phosphoribosyltransferase (NAMPT) and uses thereof | Sanford Burnham Prebys Medical Discovery Institute (US) | 2023-11-07 | — | — | US | disclosed |
| US-20230116770-A1 | SMALL MOLECULE ACTIVATORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute | 2023-04-13 | — | — | US | disclosed |
| US-11452717-B2 | Small molecule activators of nicotinamide phosphoribosyltransferase (NAMPT) and uses thereof | Sanford Burnham Prebys Medical Discovery Institute (US) | 2022-09-27 | — | — | US | disclosed |
| US-20210161873-A1 | SMALL MOLECULE ACTIVATORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute | 2021-06-03 | — | — | US | disclosed |
| US-20210161873-A1 | SMALL MOLECULE ACTIVATORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute | 2021-06-03 | — | — | US | disclosed |
| US-10752624-B2 | Kinase inhibitors | ORIGENIS GMBH (DE) | 2020-08-25 | — | — | US | disclosed |
| EP-3568390-A1 | SMALL MOLECULE ACTIVATORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2019-11-20 | — | — | EP | disclosed |
| US-5106814-A | Containing aromatic isocyanate, imino compound, trialkoxy benzoate; image stability, responsiveness | MITSUBISHI PAPER MILLS LIMITED (JP) | 1992-04-21 | — | — | US | disclosed |
| US-5098738-A | Coating a suspension of an isocyanate and an imino compound for color development and adjustment of pH with acid or base | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1992-03-24 | — | — | US | disclosed |
| US-5098881-A | A support with an aromatic isocyanate that reacts with an amine to form color and a metallic soap | MITSUBISHI PAPER MILLS LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| US-5093305-A | Phenolic Compound, Aromatic Isocyanate, Imine | MITSUBISHI PAPER MILLS LIMITED (JP) | 1992-03-03 | — | — | US | disclosed |
| US-5079211-A | Reduced fogging, image storage stability, thermal printing | MITSUBISHI PAPER MILLS LIMITED (JP) | 1992-01-07 | — | — | US | disclosed |
| US-5043315-A | Aromatic or heterocyclic isocyanate and imino compound | MITSUBISHI PAPER MILLS LIMITED (JP) | 1991-08-27 | — | — | US | disclosed |
| US-5043312-A | Mixture of imino and isocyanate compounds, biphenyl alcohol in binder on support; image preservation, heat responsiveness | MITSUBISHI PAPER MILLS LIMITED (JP) | 1991-08-27 | — | — | US | disclosed |
| EP-0439638-A1 | Heat sensitive recording material | MITSUBISHI PAPER MILLS, LTD. (JP) | 1991-08-07 | — | — | EP | disclosed |
| US-5036039-A | Aromatic isocyanate and imine | MITSUBISHI PAPER MILLS LIMITED (JP) | 1991-07-30 | — | — | US | disclosed |
| US-4965237-A | AROMATICITY-POSESSING ISOCYANATE COMPOUND, IMINO COMPOUND, AND ANILINE DERIVATIVE | MITSUBISHI PAPER MILLS, LTD. (JP) | 1990-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11452717-B2 | Small molecule activators of nicotinamide phosphoribosyltransferase (NAMPT) and uses thereof | NAMPT, NAPRT, NNT | KMT2A 828/4885MEN1 2154/4885POLB 1482/4885 |
| US-20210161873-A1 | SMALL MOLECULE ACTIVATORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) AND USES THEREOF | NAMPT, NAPRT, NNT | KMT2A 828/4885MEN1 2154/4885POLB 1482/4885 |
| US-11806337-B2 | Small molecule activators of nicotinamide phosphoribosyltransferase (NAMPT) and uses thereof | NAMPT, NAPRT, NNT | KMT2A 828/4885MEN1 2154/4885POLB 1482/4885 |
| US-20230116770-A1 | SMALL MOLECULE ACTIVATORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) AND USES THEREOF | NAMPT, NAPRT, NNT | KMT2A 828/4885MEN1 2154/4885POLB 1482/4885 |
| US-10752624-B2 | Kinase inhibitors | LRRK2, MYLK2, MYLK | KMT2A 929/4885MEN1 636/4885POLB 3175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.