Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.44 |
| ▸ | HTR2A | P28223 | 5/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | COASY | Q13057 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6841274 | 0.81 | SLC6A4 (0.55) | SLC6A4HTR2AKCNH2ADRB2SLC6A2 | |
| SCHEMBL8246636 | 0.81 | COASY (0.44) | SLC6A4ADRB2ADRB1ADRB3SLC6A2 | |
| SCHEMBL178548 | 0.81 | COASY (0.44) | SLC6A4ADRB2ADRB1ADRB3SLC6A2 | |
| SCHEMBL6841228 | 0.81 | HTR2A (0.44) | SLC6A4HTR2AKCNH2SLC6A2ALDH1A1 | |
| SCHEMBL6841275 | 0.81 | HTR2A (0.44) | SLC6A4HTR2AKCNH2SLC6A2ALDH1A1 | |
| SCHEMBL6837048 | 0.81 | HTR2A (0.44) | SLC6A4HTR2AKCNH2SLC6A2ALDH1A1 | |
| SCHEMBL6842074 | 0.81 | HTR2A (0.44) | SLC6A4HTR2AKCNH2SLC6A2ALDH1A1 | |
| SCHEMBL6842018 | 0.81 | HTR2A (0.44) | SLC6A4HTR2AKCNH2SLC6A2ALDH1A1 | |
| SCHEMBL6842242 | 0.81 | ALDH1A1 (0.42) | SLC6A4HTR2AKCNH2SLC6A2ALDH1A1 | |
| SCHEMBL6841425 | 0.81 | SLC6A4 (0.55) | SLC6A4HTR2AKCNH2SLC6A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759435-B1 | SUCH AS METHYL-(1-(2-(1-PHENYL-ETHYL)-PHENYL)-ETHYL)-AMINE; SEROTONIN REUPTAKE INHIBITORS | A.P. Group Inc. | 2004-07-06 | — | — | US | claimed |
| US-6759435-B1 | SUCH AS METHYL-(1-(2-(1-PHENYL-ETHYL)-PHENYL)-ETHYL)-AMINE; SEROTONIN REUPTAKE INHIBITORS | A.P. Group Inc. | 2004-07-06 | — | — | US | disclosed |