Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.55 |
| ▸ | HTR2A | P28223 | 6/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | CNR1 | P21554 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6841228 | 0.85 | HTR2A (0.44) | SLC6A4HTR2AKCNH2TSHRSLC6A2 | |
| SCHEMBL6842018 | 0.85 | HTR2A (0.44) | SLC6A4HTR2AKCNH2TSHRSLC6A2 | |
| SCHEMBL6841275 | 0.85 | HTR2A (0.44) | SLC6A4HTR2AKCNH2TSHRSLC6A2 | |
| SCHEMBL6837048 | 0.85 | HTR2A (0.44) | SLC6A4HTR2AKCNH2TSHRSLC6A2 | |
| SCHEMBL6842074 | 0.85 | HTR2A (0.44) | SLC6A4HTR2AKCNH2TSHRSLC6A2 | |
| SCHEMBL6841574 | 0.82 | SMN1; SMN2 (0.41) | SLC6A4HTR2AKCNH2CNR1SLC6A2 | |
| SCHEMBL6841425 | 0.81 | SLC6A4 (0.55) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL6841214 | 0.81 | SLC6A4 (0.44) | SLC6A4HTR2AKCNH2SLC6A2KDM4E | |
| Hydrochloric Acid SCHEMBL6836835 | 0.80 | SLC6A4 (0.54) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL6843796 | 0.79 | CYP2D6 (0.54) | SLC6A4HTR2AKCNH2CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759435-B1 | SUCH AS METHYL-(1-(2-(1-PHENYL-ETHYL)-PHENYL)-ETHYL)-AMINE; SEROTONIN REUPTAKE INHIBITORS | A.P. Group Inc. | 2004-07-06 | — | — | US | claimed |
| US-6759435-B1 | SUCH AS METHYL-(1-(2-(1-PHENYL-ETHYL)-PHENYL)-ETHYL)-AMINE; SEROTONIN REUPTAKE INHIBITORS | A.P. Group Inc. | 2004-07-06 | — | — | US | disclosed |