Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | RGS12 | O14924 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6841228 | 1.00 | HTR2A (0.44) | HTR2ACYP2D6CHRM2ADRA1ACYP3A4 | |
| SCHEMBL6841275 | 1.00 | HTR2A (0.44) | HTR2ACYP2D6CHRM2ADRA1ACYP3A4 | |
| SCHEMBL6837048 | 1.00 | HTR2A (0.44) | HTR2ACYP2D6CHRM2ADRA1ACYP3A4 | |
| SCHEMBL6842074 | 1.00 | HTR2A (0.44) | HTR2ACYP2D6CHRM2ADRA1ACYP3A4 | |
| SCHEMBL6841274 | 0.85 | SLC6A4 (0.55) | HTR2ACYP2D6CHRM2ADRA1ACYP3A4 | |
| SCHEMBL6841574 | 0.85 | SMN1; SMN2 (0.41) | HTR2ACYP2D6SLC6A4KCNH2LMNA | |
| SCHEMBL4658430 | 0.84 | TYR (0.54) | CYP2D6CYP2C9TSHRADRA2CTYR | |
| SCHEMBL6843796 | 0.82 | CYP2D6 (0.54) | HTR2ACYP2D6CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL6841238 | 0.81 | TYR (0.42) | HTR2ACYP2D6CHRM2ADRA1ACYP3A4 | |
| SCHEMBL6836923 | 0.81 | CASR (0.41) | HTR2ACYP2D6CHRM2ADRA1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759435-B1 | SUCH AS METHYL-(1-(2-(1-PHENYL-ETHYL)-PHENYL)-ETHYL)-AMINE; SEROTONIN REUPTAKE INHIBITORS | A.P. Group Inc. | 2004-07-06 | — | — | US | disclosed |