Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | NAMPT | P43490 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14185462 | 0.83 | LMNA (0.59) | ATMGAALMNAIRAK4 | |
| SCHEMBL442079 | 0.81 | ATM (0.51) | ATMNAMPTRAB9ANPC1GAA | |
| SCHEMBL17999731 | 0.80 | ATM (0.49) | ATMNAMPTRAB9ANPC1GAA | |
| SCHEMBL10138770 | 0.76 | GAA (0.50) | ATMNAMPTRAB9ANPC1GAA | |
| SCHEMBL11541530 | 0.75 | GAA (0.73) | ATMNAMPTRAB9ANPC1GAA | |
| SCHEMBL1085423 | 0.74 | ATM (0.68) | ATMNAMPTRAB9AGAAALDH1A1 | |
| SCHEMBL22987577 | 0.73 | GAA (0.59) | ATMNAMPTRAB9ANPC1GAA | |
| SCHEMBL8568083 | 0.73 | GAA (0.69) | ATMNAMPTRAB9ANPC1GAA | |
| SCHEMBL27716559 | 0.72 | ATM (0.65) | ATMNAMPTRAB9ANPC1GAA | |
| SCHEMBL12921935 | 0.72 | ATM (0.69) | ATMNAMPTRAB9ANPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010252-A1 | FUNGICIDAL MIXTURES OF THIOPHENE DERIVATIVE | FOOR STEPHEN RAY (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010252-A1 | FUNGICIDAL MIXTURES OF THIOPHENE DERIVATIVE | MRM1, CYP11B1, CYP11A1 | ATM 3892/4885NAMPT 2344/4885RAB9A 2639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.