Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3678118 | 0.86 | MAPT (0.48) | MAPTCYP3A4ACHEALOX5PTGS2 | |
| SCHEMBL14511731 | 0.84 | CYP3A4 (0.50) | MAPTCYP3A4ACHEALOX5CA9 | |
| SCHEMBL1808984 | 0.82 | EPHX2 (0.49) | MAPTCYP3A4ACHEALOX5PTGS2 | |
| SCHEMBL4127825 | 0.82 | MAPT (0.54) | MAPTCYP3A4ACHEALOX5PTGS2 | |
| SCHEMBL70823 | 0.81 | MAPT (0.58) | MAPTCYP3A4ACHEALOX5PTGS2 | |
| SCHEMBL2115984 | 0.80 | CYP3A4 (0.46) | MAPTCYP3A4ACHEALOX5PTGS2 | |
| Benzene SCHEMBL28616661 | 0.78 | EPHX2 (0.46) | MAPTCYP3A4ACHEALOX5PTGS2 | |
| Isoespintanol SCHEMBL17442883 | 0.78 | AKR1B1 (0.42) | MAPTCYP3A4ACHEPTGS2EPHX2 | |
| SCHEMBL4472439 | 0.77 | EPHX2 (0.57) | MAPTCYP3A4ACHEALOX5CA9 | |
| SCHEMBL29421891 | 0.77 | EPHX2 (0.57) | MAPTCYP3A4ACHEALOX5CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109276563-B | Application of pharmaceutical composition in preparing medicine for treating or preventing individual infection virus | 珠海市鑫展生物科技有限公司 | 2021-04-09 | — | — | CN | claimed |
| CN-109276563-B | Application of pharmaceutical composition in preparing medicine for treating or preventing individual infection virus | 珠海市鑫展生物科技有限公司 | 2021-04-09 | — | — | CN | disclosed |
| US-20130129832-A1 | COGNITIVE IMPAIRMENT AMELIORANT | TOHOKU UNIVERSITY (JP) | 2013-05-23 | — | — | US | disclosed |
| US-20110287106-A1 | COGNITIVE IMPAIRMENT AMELIORANT | JAPAN ROYAL JELLEY CO., LTD. (JP) | 2011-11-24 | — | — | US | disclosed |
| US-20110137050-A1 | Process for the Preparation of 4,7-Dimethoxy-5-Methyl-1,3-Benzodioxole and Derivatives Thereof | YONG CHUN PROSPEROUS BIOTECH CO. (TW) | 2011-06-09 | — | — | US | disclosed |
| US-20110137050-A1 | Process for the Preparation of 4,7-Dimethoxy-5-Methyl-1,3-Benzodioxole and Derivatives Thereof | YONG CHUN PROSPEROUS BIOTECH CO. (TW) | 2011-06-09 | — | — | US | disclosed |
| US-20110137050-A1 | Process for the Preparation of 4,7-Dimethoxy-5-Methyl-1,3-Benzodioxole and Derivatives Thereof | YONG CHUN PROSPEROUS BIOTECH CO. (TW) | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130129832-A1 | COGNITIVE IMPAIRMENT AMELIORANT | CHAT, ACHE, PSEN1 | MAPT 7/4885CYP3A4 4098/4885ACHE 2/4885 |
| US-20110137050-A1 | Process for the Preparation of 4,7-Dimethoxy-5-Methyl-1,3-Benzodioxole and Derivatives Thereof | DAO, F7, LOX | MAPT 4875/4885CYP3A4 284/4885ACHE 3312/4885 |
| US-20110287106-A1 | COGNITIVE IMPAIRMENT AMELIORANT | CHAT, ACHE, PSEN1 | MAPT 7/4885CYP3A4 4098/4885ACHE 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.