Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | RECQL | P46063 | 1/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.64 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.64 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.64 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.64 |
| ▸ | TAS2R31 | P59538 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30082747 | 0.90 | ALDH1A1 (0.79) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL678646 | 0.90 | ALDH1A1 (0.79) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| Sudachitin SCHEMBL29435872 | 0.88 | ALDH1A1 (0.84) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| Sudachitin SCHEMBL6361479 | 0.88 | ALDH1A1 (0.84) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL10997922 | 0.88 | ALDH1A1 (0.80) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL20530430 | 0.85 | ALDH1A1 (0.84) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL10997058 | 0.85 | ALDH1A1 (0.88) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| Isothymonin SCHEMBL29291573 | 0.84 | ALDH1A1 (1.00) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| Isothymonin SCHEMBL30601620 | 0.84 | ALDH1A1 (1.00) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL30954258 | 0.82 | MEN1 (0.71) | ALDH1A1MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130129832-A1 | COGNITIVE IMPAIRMENT AMELIORANT | TOHOKU UNIVERSITY (JP) | 2013-05-23 | — | — | US | disclosed |
| US-20110287106-A1 | COGNITIVE IMPAIRMENT AMELIORANT | JAPAN ROYAL JELLEY CO., LTD. (JP) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130129832-A1 | COGNITIVE IMPAIRMENT AMELIORANT | CHAT, ACHE, PSEN1 | ALDH1A1 2200/4885MAPT 7/4885KDM4E 1500/4885 |
| US-20110287106-A1 | COGNITIVE IMPAIRMENT AMELIORANT | CHAT, ACHE, PSEN1 | ALDH1A1 2200/4885MAPT 7/4885KDM4E 1500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.