Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 12/20 | 0.53 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.48 |
| ▸ | PKN1 | Q16512 | 3/20 | 0.47 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.47 |
| ▸ | PIM1 | P11309 | 2/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.46 |
| ▸ | BRSK1 | Q8TDC3 | 2/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | PLK4 | O00444 | 1/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6841863 | 0.78 | RIPK1 (0.48) | PARP1RIPK1PKN1PKN2PIM1 | |
| SCHEMBL6841123 | 0.75 | PIM1 (0.61) | PARP1RIPK1PIM1PIM3BRSK1 | |
| SCHEMBL6843631 | 0.74 | PARP1 (0.59) | PARP1CHEK2RPS6KB1PARP2 | |
| SCHEMBL30225827 | 0.73 | PARP1 (0.57) | PARP1RIPK1 | |
| SCHEMBL6842025 | 0.73 | PARP1 (0.66) | PARP1PKN1PKN2PIM1PIM3 | |
| SCHEMBL2927616 | 0.70 | PARP1 (0.60) | PARP1PKN1PKN2PIM1PIM3 | |
| SCHEMBL1933246 | 0.66 | PARP1 (0.69) | PARP1PKN1PKN2PIM1PIM3 | |
| SCHEMBL16497016 | 0.66 | PARP1 (0.69) | PARP1PKN1PKN2PIM1PIM3 | |
| SCHEMBL6842051 | 0.66 | PARP1 (0.69) | PARP1PKN1PKN2PIM1PIM3 | |
| SCHEMBL2755855 | 0.66 | QPCT (0.71) | HRH3CYP3A4CYP2D6TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040034078-A1 | Benzimidazole inhibitors of poly(ADP-ribosyl) polymerase | AGOURON PHARMACEUTICALS, INC. | 2004-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034078-A1 | Benzimidazole inhibitors of poly(ADP-ribosyl) polymerase | PARP1, PARP11, PARP2 | TDP1 31/4885PARP1 1/4885RIPK1 1119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.