Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 4/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6842074 | 0.82 | HTR2A (0.44) | CYP2D6HTR2ASLC6A4ALDH1A1KCNH2 | |
| SCHEMBL6841228 | 0.82 | HTR2A (0.44) | CYP2D6HTR2ASLC6A4ALDH1A1KCNH2 | |
| SCHEMBL6841275 | 0.82 | HTR2A (0.44) | CYP2D6HTR2ASLC6A4ALDH1A1KCNH2 | |
| SCHEMBL6837048 | 0.82 | HTR2A (0.44) | CYP2D6HTR2ASLC6A4ALDH1A1KCNH2 | |
| SCHEMBL6842018 | 0.82 | HTR2A (0.44) | CYP2D6HTR2ASLC6A4ALDH1A1KCNH2 | |
| SCHEMBL6841274 | 0.79 | SLC6A4 (0.55) | CYP2D6HTR2ASLC6A4ALDH1A1KCNH2 | |
| SCHEMBL6841574 | 0.79 | SMN1; SMN2 (0.41) | CYP2D6HTR2ASLC6A4ALDH1A1KCNH2 | |
| SCHEMBL327954 | 0.78 | CA1 (0.56) | CYP2D6ALDH1A1CA1CA2ACHE | |
| SCHEMBL13462356 | 0.78 | CA1 (0.56) | CYP2D6ALDH1A1CA1CA2ACHE | |
| SCHEMBL8239398 | 0.78 | CA1 (0.56) | CYP2D6ALDH1A1CA1CA2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759435-B1 | SUCH AS METHYL-(1-(2-(1-PHENYL-ETHYL)-PHENYL)-ETHYL)-AMINE; SEROTONIN REUPTAKE INHIBITORS | A.P. Group Inc. | 2004-07-06 | — | — | US | claimed |
| US-6759435-B1 | SUCH AS METHYL-(1-(2-(1-PHENYL-ETHYL)-PHENYL)-ETHYL)-AMINE; SEROTONIN REUPTAKE INHIBITORS | A.P. Group Inc. | 2004-07-06 | — | — | US | disclosed |