Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6841228 | 0.85 | HTR2A (0.44) | SLC6A4HTR2ALMNAALDH1A1SLC6A2 | |
| SCHEMBL6837048 | 0.85 | HTR2A (0.44) | SLC6A4HTR2ALMNAALDH1A1SLC6A2 | |
| SCHEMBL6841275 | 0.85 | HTR2A (0.44) | SLC6A4HTR2ALMNAALDH1A1SLC6A2 | |
| SCHEMBL6842074 | 0.85 | HTR2A (0.44) | SLC6A4HTR2ALMNAALDH1A1SLC6A2 | |
| SCHEMBL6842018 | 0.85 | HTR2A (0.44) | SLC6A4HTR2ALMNAALDH1A1SLC6A2 | |
| SCHEMBL6841274 | 0.82 | SLC6A4 (0.55) | SLC6A4HTR2ALMNAALDH1A1SLC6A2 | |
| SCHEMBL6842242 | 0.81 | ALDH1A1 (0.42) | SLC6A4HTR2ALMNAALDH1A1SLC6A2 | |
| SCHEMBL6843796 | 0.79 | CYP2D6 (0.54) | SLC6A4HTR2ALMNAALDH1A1KCNH2 | |
| SCHEMBL6836923 | 0.78 | CASR (0.41) | SMN1; SMN2SLC6A4HTR2ALMNAALDH1A1 | |
| SCHEMBL10087237 | 0.76 | ALDH1A1 (0.50) | SMN1; SMN2LMNAALDH1A1CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759435-B1 | SUCH AS METHYL-(1-(2-(1-PHENYL-ETHYL)-PHENYL)-ETHYL)-AMINE; SEROTONIN REUPTAKE INHIBITORS | A.P. Group Inc. | 2004-07-06 | — | — | US | claimed |
| US-6759435-B1 | SUCH AS METHYL-(1-(2-(1-PHENYL-ETHYL)-PHENYL)-ETHYL)-AMINE; SEROTONIN REUPTAKE INHIBITORS | A.P. Group Inc. | 2004-07-06 | — | — | US | disclosed |