Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2800883 | 0.85 | HRH3 (0.53) | SLC6A2SLC6A4HRH3DRD2DRD3 | |
| SCHEMBL13196798 | 0.85 | HRH3 (0.53) | SLC6A2SLC6A4HRH3DRD2DRD3 | |
| SCHEMBL2800881 | 0.85 | HRH3 (0.53) | SLC6A2SLC6A4HRH3DRD2DRD3 | |
| SCHEMBL6839707 | 0.84 | HRH3 (0.54) | HRH3DRD2DRD3KMT2AL3MBTL1 | |
| SCHEMBL6839703 | 0.84 | HRH3 (0.54) | HRH3DRD2DRD3KMT2AL3MBTL1 | |
| SCHEMBL6839704 | 0.84 | HRH3 (0.54) | HRH3DRD2DRD3KMT2AL3MBTL1 | |
| SCHEMBL7022189 | 0.84 | HRH3 (0.54) | HRH3DRD2DRD3KMT2AL3MBTL1 | |
| SCHEMBL6982455 | 0.81 | DRD2 (0.45) | HRH3DRD2DRD3CACNA1FCACNA1D | |
| SCHEMBL6982450 | 0.81 | DRD2 (0.45) | HRH3DRD2DRD3CACNA1FCACNA1D | |
| SCHEMBL6982459 | 0.81 | DRD2 (0.45) | HRH3DRD2DRD3CACNA1FCACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1496361-A | Phenyl derivatives 3 | Ĭ��ר���ɷ�����˾ | 2004-05-12 | — | — | CN | disclosed |
| US-20040082563-A1 | Phenyl derivatives 3 | MERCK PATENT GMBH (DE) | 2004-04-29 | — | — | US | disclosed |
| EP-1368341-A1 | PHENYL DERIVATIVES 3 | MERCK PATENT GmbH (DE) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002074765-A1 | PHENYL DERIVATIVES 3 | MERCK PATENT GMBH (DE) | 2002-09-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082563-A1 | Phenyl derivatives 3 | F2, F11, F12 | SLC6A2 4483/4885SLC6A4 4440/4885HRH3 1000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.