SCHEMBL6842288

SCHEMBL6842288

CCOc1cc(OCC)c([N+]#N)c(OCC)c1.Cc1cc(C)c(S(=O)(=O)[O-])c(C)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.34
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
RAPGEF4 Q8WZA2 2/20 0.34
KAT6A Q92794 2/20 0.34
LMNA P02545 6/20 0.33
MAPT P10636 3/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
XBP1 P17861 1/20 0.33
HTT P42858 4/20 0.32
ALDH1A1 P00352 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
TSHR P16473 2/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6847398 0.84 PLA2G2A (0.39) MAPK1MAPTGAAALDH1A1CA12
SCHEMBL92011 0.78 NQO1 (0.41) MAPK1KMT2AMEN1LMNAMAPT
SCHEMBL4074936 0.75 MAPT (0.37) MAPK1KMT2AMEN1LMNAMAPT
SCHEMBL13890811 0.74 RXFP1 (0.36) MAPK1KMT2AMEN1MAPTPOLB
SCHEMBL14178558 0.73 KDM4E (0.39) MAPK1KMT2ALMNAMAPTGAA
SCHEMBL6848210 0.72 CA2 (0.42) LMNAMAPTHTTSMN1; SMN2CA12
Silver SCHEMBL9243729 0.68 RAPGEF4 (0.54) MAPK1RAPGEF4LMNAPOLBGAA
SCHEMBL9165326 0.68 RAPGEF4 (0.54) MAPK1RAPGEF4LMNAPOLBGAA
SCHEMBL1499866 0.68 RAPGEF4 (0.54) MAPK1RAPGEF4LMNAMAPTPOLB
SCHEMBL6274955 0.68 RAPGEF4 (0.54) MAPK1RAPGEF4LMNAPOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6699638-B2 ON A THERMAL CROSSLINKING LAYER A WATER SOLUBLE OVERCOAT LAYER, AND AT LEAST ONE OF THESE LAYERS CONTAINS A COMPOUND CAPABLE OF CONVERTING LIGHT INTO HEAT; EASY TO HANDLE AND CAUSES NO DEFECTS EVEN WHEN TOUCHED WITH FINGERS FUJI PHOTO FILM CO., LTD. (JP) 2004-03-02 US disclosed
EP-0899614-B1 Image recording material FUJI PHOTO FILM CO LTD (JP) 2002-01-09 EP disclosed
US-6162574-A Image recording material FUJI PHOTO FILM CO., LTD. (JP) 2000-12-19 US disclosed
EP-0899614-A1 Image recording material Fuji Photo Film Co., Ltd. (JP) 1999-03-03 EP disclosed