Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9467 | 1.00 | ALDH1A1 (0.33) | ALDH1A1MAPTMAPK1GAATSHR | |
| SCHEMBL16412265 | 0.95 | PIK3CD (0.31) | ALDH1A1MAPTMAPK1 | |
| SCHEMBL6842512 | 0.93 | ALDH1A1 (0.37) | ALDH1A1MAPTGAA | |
| SCHEMBL17777960 | 0.91 | FDPS (0.36) | GAATSHRCYP1A2CYP2C9HSD17B10 | |
| SCHEMBL9554 | 0.90 | ALDH1A1 (0.33) | ALDH1A1MAPK1GAATSHR | |
| SCHEMBL13291449 | 0.89 | CYP1A2 (0.44) | ALDH1A1MAPK1CYP1A2CYP2C9HPGD | |
| SCHEMBL1024925 | 0.87 | ALDH1A1 (0.35) | ALDH1A1MAPK1GAATSHR | |
| SCHEMBL3429386 | 0.86 | PIK3CD (0.31) | MAPT | |
| SCHEMBL24641232 | 0.84 | — | — | |
| SCHEMBL8571 | 0.84 | MAPT (0.36) | MAPTMAPK1CYP1A2CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787592-B1 | OLEOPHILIC NANOCOMPOSITES | SOUTHERN CLAY PRODUCTS, INC. | 2004-09-07 | — | — | US | claimed |
| US-6037315-A | QUATERNARY AMMONIUM SALT COMPRISING MIXTURE OF MONO-, DI- AND TRI-ESTER COMPONENTS; USED AS A FABRIC SOFTENER AND AS A HAIR AND SKIN CONDITIONER | AKZO NOBEL NV (NL) | 2000-03-14 | — | — | US | claimed |
| CN-118638523-A | Cold plate type cooling liquid composition applied to liquid cooling battery energy storage system | 统一石油化工有限公司 | 2024-09-13 | — | — | CN | disclosed |
| EP-3546549-B1 | LUBRICATING OIL COMPOSITION | INFINEUM INT LTD (GB) | 2022-11-09 | — | — | EP | disclosed |
| WO-2021132252-A1 | FLUORINE-CONTAINING ETHER COMPOUND, LUBRICANT FOR MAGNETIC RECORDING MEDIA, AND MAGNETIC RECORDING MEDIUM | 昭和電工株式会社 | 2021-07-01 | — | — | WO | disclosed |
| US-20190300810-A1 | Lubricating Oil Composition | INFINEUM INTERNATIONAL LIMITED (GB) | 2019-10-03 | — | — | US | disclosed |
| US-8044213-B2 | Thiazolyl-benzimidazoles | HOFFMANN-LA ROCHE INC. (US) | 2011-10-25 | — | — | US | disclosed |
| US-20100160308-A1 | Thiazolyl-Benzimidazoles | CAI JIANPING | 2010-06-24 | — | — | US | disclosed |
| US-7402583-B2 | Substituted quinolines as antitumor agents | ASTRZENCA AB (SE) | 2008-07-22 | — | — | US | disclosed |
| US-7402583-B2 | Substituted quinolines as antitumor agents | ASTRZENCA AB (SE) | 2008-07-22 | — | — | US | disclosed |
| US-20070027318-A1 | Quinoline derivatives and quinazoline derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 2007-02-01 | — | — | US | disclosed |
| US-7169789-B2 | Quinoline derivatives and quinazoline derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 2007-01-30 | — | — | US | disclosed |
| US-20070021407-A1 | Substituted quinolines as antitumor agents | ASTRAZENECA | 2007-01-25 | — | — | US | disclosed |
| US-20070021407-A1 | Substituted quinolines as antitumor agents | ASTRAZENECA | 2007-01-25 | — | — | US | disclosed |
| US-6787592-B1 | OLEOPHILIC NANOCOMPOSITES | SOUTHERN CLAY PRODUCTS, INC. | 2004-09-07 | — | — | US | disclosed |
| US-6770608-B2 | TEXTILE SOFTENING; HAIR AND SKIN CONDITIONER | AKZO NOBEL N.V. (NL) | 2004-08-03 | — | — | US | disclosed |
| US-20020025915-A1 | High Di(alkyl fatty ester) amines and quaternary ammonium compounds derived therefrom | AKZO NOBEL N.V. (NL) | 2002-02-28 | — | — | US | disclosed |
| US-6323167-B1 | COMPOSITIONS WHICH COMPRISE QUATERNARY AMMONIUM BASED SOFTENING AGENTS WHICH ARE HIGH IN DIESTER AND LOW IN TRIESTER CONTENT | AKZO NOBEL N.V. (NL) | 2001-11-27 | — | — | US | disclosed |
| WO-2001028924-A1 | ORGANOCLAY COMPOSITIONS PREPARED FROM ESTER QUATS AND COMPOSITES BASED ON THE COMPOSITIONS | SOUTHERN CLAY PRODUCTS, INC. (US) | 2001-04-26 | — | — | WO | disclosed |
| US-6037315-A | QUATERNARY AMMONIUM SALT COMPRISING MIXTURE OF MONO-, DI- AND TRI-ESTER COMPONENTS; USED AS A FABRIC SOFTENER AND AS A HAIR AND SKIN CONDITIONER | AKZO NOBEL NV (NL) | 2000-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021407-A1 | Substituted quinolines as antitumor agents | NR1H3, NR1H2, NR0B1 | ALDH1A1 3767/4885MAPT 4728/4885MAPK1 3086/4885 |
| US-20070027318-A1 | Quinoline derivatives and quinazoline derivatives | CYTH3, NQO2, NRAS | ALDH1A1 3029/4885MAPT 4850/4885MAPK1 3633/4885 |
| US-20100160308-A1 | Thiazolyl-Benzimidazoles | CYP3A7, CYP2C19, CYP3A5 | ALDH1A1 100/4885MAPT 1573/4885MAPK1 3728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.