Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9273390 | 0.76 | MCL1 (0.39) | KMT2AALDH1A1POLBHPGDTSHR | |
| SCHEMBL7258261 | 0.75 | PARP1 (0.36) | KMT2AALDH1A1LMNAHIF1APOLB | |
| SCHEMBL9037611 | 0.66 | MCL1 (0.34) | TSHR | |
| SCHEMBL28414326 | 0.64 | NOTUM (0.31) | ALDH1A1HPGD | |
| SCHEMBL30533390 | 0.64 | LMNA (0.81) | MEN1KMT2ANPC1ALDH1A1LMNA | |
| SCHEMBL13270663 | 0.63 | ALDH1A1 (0.56) | NPSR1MEN1KMT2ATDP1NPC1 | |
| SCHEMBL30540811 | 0.63 | CA12 (0.39) | MEN1KMT2ANPC1ALDH1A1NAMPT | |
| SCHEMBL6757896 | 0.62 | MAPT (0.58) | NPSR1MEN1KMT2ATDP1NPC1 | |
| SCHEMBL23540740 | 0.62 | LMNA (0.71) | LMNARAB9APOLBHPGDCYP2C19 | |
| SCHEMBL30043036 | 0.62 | LMNA (0.71) | LMNARAB9APOLBHPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1299395-B1 | OXAZINOQUINOLONES USEFUL FOR THE TREATMENT OF VIRAL INFECTIONS | UPJOHN CO (US) | 2004-09-15 | — | — | EP | claimed |