Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9273390 | 0.80 | MCL1 (0.39) | MCL1NOTUMRIPK1PRMT5AHR | |
| SCHEMBL7258261 | 0.76 | PARP1 (0.36) | MCL1NOTUMRIPK1PRMT5AHR | |
| SCHEMBL6843181 | 0.66 | NPSR1 (0.45) | TSHR | |
| SCHEMBL28414326 | 0.66 | NOTUM (0.31) | NOTUMKDM4E | |
| SCHEMBL31256805 | 0.64 | ITGB2 (0.33) | NOTUMAHR | |
| SCHEMBL30540811 | 0.62 | CA12 (0.39) | KDM4ETSHR | |
| SCHEMBL29501124 | 0.61 | RIPK1 (0.54) | NOTUMRIPK1AHRKDM4E | |
| SCHEMBL17957763 | 0.61 | RIPK1 (0.54) | NOTUMRIPK1AHRKDM4E | |
| SCHEMBL5218968 | 0.60 | MTNR1A (0.54) | KDM4E | |
| SCHEMBL11202182 | 0.60 | NOTUM (0.39) | MCL1NOTUMKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705828-A1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |