Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 5/20 | 0.40 |
| ▸ | NOS2 | P35228 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14589007 | 0.87 | NPC1 (0.40) | NOS3NOS2NPC1CASP3RAB9A | |
| SCHEMBL14457936 | 0.86 | NOS3 (0.50) | NOS3NOS2TAAR1KIF11NOS1 | |
| SCHEMBL14457964 | 0.86 | MAOB (0.43) | — | |
| SCHEMBL14457891 | 0.86 | ALDH1A1 (0.40) | NPC1RAB9ACNR1CNR2 | |
| SCHEMBL14588808 | 0.85 | KDM1A (0.42) | NOS3NOS2NPC1CASP3RAB9A | |
| SCHEMBL4142328 | 0.85 | NOS3 (0.40) | NOS3NOS2NPC1RAB9ATAAR1 | |
| SCHEMBL7043206 | 0.85 | NOS3 (0.40) | NOS3NOS2KIF11NOS1 | |
| SCHEMBL14540973 | 0.85 | NOS3 (0.40) | NOS3NOS2KIF11NOS1 | |
| SCHEMBL14540777 | 0.85 | NOS3 (0.40) | NOS3NOS2TAAR1KIF11NOS1 | |
| SCHEMBL14063637 | 0.85 | NOS3 (0.40) | NOS3NOS2TAAR1KIF11NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040054194-A1 | Method for producing 1-pyrrolines | BAYER CROPSCIENCE AG (DE) | 2004-03-18 | — | — | US | disclosed |
| EP-1322606-A1 | METHOD FOR PRODUCING DELTA 1 -PYRROLINES | Bayer CropScience AG (DE) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002024642-A1 | METHOD FOR PRODUCING Δ1-PYRROLINES | BAYER CROPSCIENCE AG (DE) | 2002-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040054194-A1 | Method for producing 1-pyrrolines | NAT1, NR5A1, CYP1B1 | NOS3 2056/4885NOS2 999/4885NPC1 1822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.