Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.40 |
| ▸ | NOS2 | P35228 | 3/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 5/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.33 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5218292 | 1.00 | NOS3 (0.40) | NOS3NOS2TAAR1NPC1RAB9A | |
| SCHEMBL14457975 | 0.96 | NOS3 (0.37) | NOS3NOS2TAAR1NPC1RAB9A | |
| SCHEMBL14457936 | 0.86 | NOS3 (0.50) | NOS3NOS2TAAR1KIF11MAPT | |
| SCHEMBL14588923 | 0.85 | KDM1A (0.33) | NOS3NOS2KDM1AMAOBPTGES | |
| SCHEMBL14540777 | 0.85 | NOS3 (0.40) | NOS3NOS2TAAR1KIF11MAOB | |
| SCHEMBL6843372 | 0.85 | NOS3 (0.40) | NOS3NOS2TAAR1NPC1RAB9A | |
| SCHEMBL14540973 | 0.85 | NOS3 (0.40) | NOS3NOS2KIF11NOS1 | |
| SCHEMBL7043206 | 0.85 | NOS3 (0.40) | NOS3NOS2KIF11MAOBNOS1 | |
| SCHEMBL14063637 | 0.85 | NOS3 (0.40) | NOS3NOS2TAAR1KIF11MAOB | |
| SCHEMBL14588993 | 0.84 | NOS3 (0.34) | NOS3NOS2NPC1RAB9ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090012144-A1 | Optically active 2,5-bisaryl-delta¹ -pyrrolines and their use as pest control agents | PLANT ANDREW | 2009-01-08 | — | — | US | disclosed |
| US-20090012144-A1 | Optically active 2,5-bisaryl-delta¹ -pyrrolines and their use as pest control agents | PLANT ANDREW | 2009-01-08 | — | — | US | disclosed |
| US-7419936-B2 | Optically active 2,5-bisaryl-Δ1-pyrrolines and their use as pest control agents | BAYER CROPSCIENCE AG (DE) | 2008-09-02 | — | — | US | disclosed |
| US-7419936-B2 | Optically active 2,5-bisaryl-Δ1-pyrrolines and their use as pest control agents | BAYER CROPSCIENCE AG (DE) | 2008-09-02 | — | — | US | disclosed |
| US-20040059129-A1 | Optically active 2,5-bisaryl-delta1-pyrrolines and their use as pest control agents | BAYER CROPSCIENCE AG (DE) | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012144-A1 | Optically active 2,5-bisaryl-delta¹ -pyrrolines and their use as pest control agents | PLD1, RPS3A, AMY1A | NOS3 1921/4885NOS2 2188/4885TAAR1 1331/4885 |
| US-20040059129-A1 | Optically active 2,5-bisaryl-delta1-pyrrolines and their use as pest control agents | DDT, CRY1, PLD1 | NOS3 1932/4885NOS2 1881/4885TAAR1 893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.