SCHEMBL6843449

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6843234	0.91	NR1H4 (0.62)	NR1H4EPHX2HDAC3HDAC4HDAC1
	SCHEMBL6193266	0.89	NR1H4 (0.53)	NR1H4EPHX2MMP13PPARG
	SCHEMBL6842510	0.89	EPHX2 (0.54)	NR1H4EPHX2MMP13PPARGALDH1A1
	SCHEMBL6843355	0.89	NR1H4 (0.53)	NR1H4EPHX2HDAC3HDAC4HDAC1
	SCHEMBL6842501	0.89	NR1H4 (0.54)	NR1H4EPHX2MMP13ALDH1A1
	SCHEMBL6843392	0.88	NR1H4 (0.52)	NR1H4EPHX2MMP13
	SCHEMBL6192574	0.86	KDM4E (0.51)	NR1H4EPHX2HDAC3HDAC4HDAC1
	SCHEMBL6843043	0.86	NR1H4 (0.50)	NR1H4EPHX2HDAC1MMP13PPARG
	SCHEMBL6843264	0.86	NR1H4 (0.50)	NR1H4EPHX2CA1CA2
	SCHEMBL6838118	0.86	MMP13 (0.55)	NR1H4EPHX2HDAC1MMP13ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.