Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 10/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6843621 | 0.87 | OPRM1 (0.45) | OPRM1OPRD1CHRM3CHRM2CHRM1 | |
| SCHEMBL8603796 | 0.84 | OPRM1 (0.58) | OPRM1OPRD1SIGMAR1KCNA3 | |
| SCHEMBL6841698 | 0.83 | PTGDR2 (0.54) | OPRM1OPRD1CHRM3KCNH2 | |
| SCHEMBL6841708 | 0.83 | OPRM1 (0.52) | OPRM1CHRM3KCNH2HTR1ALMNA | |
| Hydrochloric Acid SCHEMBL8605242 | 0.83 | OPRM1 (0.56) | OPRM1CHRM3CYP2D6CHRM2CHRM1 | |
| SCHEMBL6842012 | 0.82 | OPRM1 (0.60) | OPRM1OPRD1CYP2D6CHRM2CHRM1 | |
| SCHEMBL6841131 | 0.80 | OPRM1 (0.51) | OPRM1OPRD1CHRM3KCNH2HTR1A | |
| SCHEMBL6841129 | 0.79 | OPRM1 (0.51) | OPRM1OPRD1CHRM3KCNH2CHRM4 | |
| SCHEMBL6662792 | 0.79 | OPRM1 (0.55) | OPRM1OPRD1CYP2D6CHRM2CHRM1 | |
| Desmethylmoramide SCHEMBL2111155 | 0.77 | OPRM1 (0.68) | OPRM1OPRD1CYP2D6CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040034104-A1 | 2,2-Diphenylbutanamide derivatives and medicines containing the same | SSP CO., LTD. (JP) | 2004-02-19 | — | — | US | disclosed |
| US-20040034078-A1 | Benzimidazole inhibitors of poly(ADP-ribosyl) polymerase | AGOURON PHARMACEUTICALS, INC. | 2004-02-19 | — | — | US | disclosed |
| EP-1325912-A1 | 2,2-DIPHENYLBUTANAMIDE DERIVATIVES AND MEDICINES CONTAINING THE SAME | SSP Co., Ltd. (JP) | 2003-07-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034078-A1 | Benzimidazole inhibitors of poly(ADP-ribosyl) polymerase | PARP1, PARP11, PARP2 | OPRM1 4118/4885OPRD1 3673/4885CHRM3 4862/4885 |
| US-20040034104-A1 | 2,2-Diphenylbutanamide derivatives and medicines containing the same | OPRD1, OPRM1, OPRK1 | OPRM1 2/4885OPRD1 1/4885CHRM3 343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.