Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | CHKA | P35790 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.45 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1843054 | 0.82 | — | — | |
| SCHEMBL5072572 | 0.82 | POLB (0.52) | POLBKMT2ACYP1A2 | |
| Tert-Butyl Formate SCHEMBL27990929 | 0.80 | TDP1 (0.39) | CA2CA12CA1CA9POLB | |
| SCHEMBL918917 | 0.78 | CA2 (0.50) | CA2CA12CA1CA9POLB | |
| SCHEMBL10723702 | 0.77 | CA2 (0.45) | CA2CA12CA1CA9POLB | |
| SCHEMBL8746907 | 0.77 | — | — | |
| SCHEMBL16740618 | 0.77 | KMT2A (0.45) | CA2CA12CA1CA9POLB | |
| SCHEMBL5257 | 0.76 | POLB (0.68) | CA2CA12CA1CA9POLB | |
| SCHEMBL13292855 | 0.76 | CA2 (0.48) | CA2CA12CA1CA9POLB | |
| SCHEMBL10837140 | 0.76 | CHRNB2 (0.45) | CA2CA12CA1CA9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117384140-B | Benzimidazole derivative and application thereof | 沈阳药科大学 | 2024-10-11 | — | — | CN | claimed |
| CN-117384140-A | Benzimidazole derivative and application thereof | 沈阳药科大学 | 2024-01-12 | — | — | CN | claimed |
| CN-110759911-A | Carboline derivative, preparation method thereof and application thereof in preventing and treating plant viruses, killing bacteria and killing insects | 南开大学 | 2020-02-07 | — | — | CN | claimed |
| EP-1067969-B1 | POLYENE MACROLIDE DERIVATIVES, USE FOR VECTORING MOLECULES | UNIV PARIS CURIE (FR) | 2003-07-23 | — | — | EP | claimed |
| EP-1067969-A1 | POLYENE MACROLIDE DERIVATIVES, USE FOR VECTORING MOLECULES | UNIVERSITE PIERRE ET MARIE CURIE PARIS VI (FR) | 2001-01-17 | — | — | EP | claimed |
| WO-1999051274-A1 | POLYENE MACROLIDE DERIVATIVES, USE FOR VECTORING MOLECULES | UNIVERSITE PIERRE ET MARIE CURIE (PARIS VI) (FR) | 1999-10-14 | — | — | WO | claimed |
| CN-117384140-B | Benzimidazole derivative and application thereof | 沈阳药科大学 | 2024-10-11 | — | — | CN | disclosed |
| CN-117384140-A | Benzimidazole derivative and application thereof | 沈阳药科大学 | 2024-01-12 | — | — | CN | disclosed |
| US-20190256494-A1 | PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2019-08-22 | — | — | US | disclosed |
| CN-105831175-B | A kind of liquid compound bio controls bactericide and preparation method and application more | 鞍山禾瑞生物科技有限公司 | 2018-03-20 | — | — | CN | disclosed |
| WO-2012068234-A2 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2012-05-24 | — | — | WO | disclosed |
| US-20040002465-A1 | Polyene macrolide derivatives, use for vectoring molecules | UNIVERSITE PIERRE ET MARIE CURIE (FR) | 2004-01-01 | — | — | US | disclosed |
| EP-1067969-B1 | POLYENE MACROLIDE DERIVATIVES, USE FOR VECTORING MOLECULES | UNIV PARIS CURIE (FR) | 2003-07-23 | — | — | EP | disclosed |
| EP-1067969-A1 | POLYENE MACROLIDE DERIVATIVES, USE FOR VECTORING MOLECULES | UNIVERSITE PIERRE ET MARIE CURIE PARIS VI (FR) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999051274-A1 | POLYENE MACROLIDE DERIVATIVES, USE FOR VECTORING MOLECULES | UNIVERSITE PIERRE ET MARIE CURIE (PARIS VI) (FR) | 1999-10-14 | — | — | WO | disclosed |
| US-5859011-A | Dihydropyridine derivatives as bradykinin antagonist | PFIZER INC. (US) | 1999-01-12 | — | — | US | disclosed |
| CN-1156449-A | Dihygropyridine derivatives as bradykinin antagonists | PFIZER (US) | 1997-08-06 | — | — | CN | disclosed |
| EP-0777653-A1 | DIHYGROPYRIDINE DERIVATIVES AS BRADYKININ ANTAGONISTS | PFIZER INC. (US) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996006083-A1 | 2-(PIPERAZINYL-1-CARBONYLMETHYL)-1,4-DIHYDROPYRIDINES AS BRADYKININ ANTAGONISTS | PFIZER PHARMACEUTICALS INC. (JP) | 1996-02-29 | — | — | WO | disclosed |
| WO-1996006082-A1 | DIHYDROPYRIDINE DERIVATIVES AS BRADYKININ ANTAGONISTS | PFIZER INC. (US) | 1996-02-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190256494-A1 | PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ABHD6, ABHD16A, RABL6 | CA2 4277/4885CA12 4842/4885CA1 4354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.