Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 10/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 6/20 | 0.32 |
| ▸ | HTR1B | P28222 | 5/20 | 0.32 |
| ▸ | HTR1A | P08908 | 4/20 | 0.32 |
| ▸ | HTR2C | P28335 | 3/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTR1E | P28566 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3551420 | 0.99 | HTR1F (0.36) | HTR1FRAB9ASMN1; SMN2PLATCCNT1 | |
| SCHEMBL3554804 | 0.94 | HTR1F (0.33) | HTR1FRAB9ASMN1; SMN2PLATCCNT1 | |
| Hydrochloric Acid SCHEMBL3627024 | 0.90 | HTR1F (0.41) | HTR1FHTR2AHTR1DHTR1BHTR1A | |
| SCHEMBL3548795 | 0.84 | RAB9A (0.37) | RAB9ASMN1; SMN2HTR2AHTR7LMNA | |
| Hydrochloric Acid SCHEMBL3546167 | 0.83 | RAB9A (0.37) | RAB9ASMN1; SMN2LMNA | |
| SCHEMBL3552206 | 0.81 | CYP2D6 (0.42) | HTR1FPLATHTR1DHTR1BHTR1A | |
| SCHEMBL3547115 | 0.81 | HTR1F (0.40) | HTR1FHTR2AHTR1DHTR1BHTR1A | |
| Hydrochloric Acid SCHEMBL3545956 | 0.81 | HTR1F (0.39) | HTR1FHTR2AHTR1DHTR1BHTR1A | |
| Hydrochloric Acid SCHEMBL3553017 | 0.81 | CYP2D6 (0.41) | HTR1FPLATHTR1DHTR1BHTR1A | |
| SCHEMBL3551101 | 0.78 | HTR1F (0.36) | HTR1FHTR1DHTR1BHTR2CADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392699-A1 | 6H-OXAZOLO 4,5-E]INDOLE DERIVATIVES AS NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS AND/OR SEROTONERGIC LIGANDS | MERCK PATENT GmbH (DE) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002088139-A1 | 6H-OXAZOLO[4,5-E]INDOLE DERIVATIVES AS NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS AND/OR SEROTONERGIC LIGANDS | MERCK PATENT GMBH (DE) | 2002-11-07 | — | — | WO | disclosed |