Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TK2 | O00142 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6464531 | 0.76 | TK1 (0.38) | TK1HPGDTK2 | |
| SCHEMBL5360321 | 0.74 | TK1 (0.38) | TK1MAPK1HPGDTK2 | |
| SCHEMBL5158820 | 0.73 | TK1 (0.37) | TK1HPGDTK2 | |
| SCHEMBL18648941 | 0.73 | TK1 (0.52) | TK1MAPK1HPGDTK2 | |
| SCHEMBL6837910 | 0.71 | TK1 (0.39) | TK1MAPK1HPGDTK2 | |
| SCHEMBL7761597 | 0.71 | HPGD (0.41) | TK1MAPK1HPGD | |
| SCHEMBL456749 | 0.71 | HPGD (0.57) | TK1MAPK1HPGDTK2 | |
| SCHEMBL5366622 | 0.71 | TK1 (0.38) | TK1MAPK1HPGDTK2 | |
| SCHEMBL16260046 | 0.70 | TYMP (0.46) | TK1MAPK1HPGDTK2 | |
| SCHEMBL8444389 | 0.70 | TK2 (0.36) | TK1MAPK1HPGDTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004044137-A2 | MODIFIED OLIGOMERIC COMPOUNDS AND COMPOSITIONS FOR USE IN GENE MODULATION | ISIS PHARMACEUTICALS, INC. (US) | 2004-05-27 | — | — | WO | disclosed |