Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TK2 | O00142 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5158820 | 0.85 | TK1 (0.37) | TK1HPGDTK2 | |
| SCHEMBL8642052 | 0.81 | TK1 (0.39) | TK1TK2 | |
| SCHEMBL7761597 | 0.79 | HPGD (0.41) | TK1HPGD | |
| SCHEMBL5175003 | 0.79 | KMT2A (0.40) | TK1TK2 | |
| SCHEMBL6468189 | 0.79 | TK1 (0.37) | TK1TK2 | |
| SCHEMBL6924142 | 0.77 | TK1 (0.38) | TK1HPGDTK2 | |
| SCHEMBL6513732 | 0.77 | TK1 (0.38) | TK1HPGDTK2 | |
| SCHEMBL6931032 | 0.77 | TK1 (0.38) | TK1HPGDTK2 | |
| SCHEMBL2153725 | 0.77 | TK2 (0.39) | TK1TK2 | |
| SCHEMBL6844559 | 0.76 | TK1 (0.38) | TK1HPGDTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009041-A1 | Peptide nucleic acids and synthetic procedures therefor | BUCHARDT OLE (DK) | 2005-01-13 | — | — | US | disclosed |
| US-6713602-B1 | COMPOUNDS THAT ARE NOT POLYNUCLEOTIDES YET WHICH BIND TO COMPLEMENTARY DNA AND RNA STRANDS MORE STRONGLY THE CORRESPONDING DNA | BUCHARDT OLE (DK) | 2004-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009041-A1 | Peptide nucleic acids and synthetic procedures therefor | POLRMT, CPSF7, RNGTT | TK1 290/4885HPGD 4345/4885TK2 495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.