Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL684482 | 0.86 | KDM1A (0.61) | MAPTHTTKDM4EHDAC8ALDH1A1 | |
| SCHEMBL685189 | 0.85 | GSTA1 (0.68) | MAPTHTTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12387934 | 0.79 | MAPT (0.60) | MAPTHTTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12387849 | 0.78 | KDM4E (0.64) | MAPTHTTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL685147 | 0.75 | KDM1A (0.62) | MAPTHTTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6571439 | 0.75 | KDM1A (0.62) | MAPTHTTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4907770 | 0.73 | HDAC8 (0.52) | MAPTHDAC8ALDH1A1SMN1; SMN2CASP3 | |
| SCHEMBL4907784 | 0.73 | HDAC8 (0.52) | MAPTHDAC8ALDH1A1SMN1; SMN2CASP3 | |
| SCHEMBL4910494 | 0.73 | SMN1; SMN2 (0.56) | MAPTHTTHDAC8ALDH1A1SMN1; SMN2 | |
| SCHEMBL4910489 | 0.73 | SMN1; SMN2 (0.56) | MAPTHTTHDAC8ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, SOD3 | MAPT 1491/4885HTT 386/4885KDM4E 1473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.