SCHEMBL684531

SCHEMBL684531

O=C(N/N=C/c1cc(Br)ccc1O)c1ccccc1Oc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 11/20 0.67
KMT2A Q03164 10/20 0.67
MAPT P10636 9/20 0.67
HTT P42858 7/20 0.67
LMNA P02545 5/20 0.67
SMN1; SMN2 Q16637 5/20 0.67
PGR P06401 1/20 0.67
AR P10275 1/20 0.67
ALOX12 P18054 1/20 0.67
PIK3CG P48736 1/20 0.57
RAB9A P51151 3/20 0.57
MITF O75030 3/20 0.57
NPC1 O15118 2/20 0.57
KLF5 Q13887 2/20 0.57
MEN1 O00255 6/20 0.57
ASF1A Q9Y294 2/20 0.57
TDP1 Q9NUW8 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
GPR174 Q9BXC1 1/20 0.55
POLB P06746 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1638705 0.83 KDM4E (0.79) KDM4EKMT2AMAPTHTTLMNA
SCHEMBL1638707 0.83 KDM4E (0.79) KDM4EKMT2AMAPTHTTLMNA
SCHEMBL4447019 0.83 KDM4E (0.79) KDM4EKMT2AMAPTHTTLMNA
SCHEMBL683812 0.82 KDM4E (0.77) KDM4EKMT2AMAPTHTTLMNA
SCHEMBL684930 0.82 KMT2A (0.76) KDM4EKMT2AMAPTHTTLMNA
SCHEMBL685201 0.80 KDM4E (1.00) KDM4EKMT2AMAPTHTTLMNA
SCHEMBL684521 0.80 KDM4E (0.74) KDM4EKMT2AMAPTHTTLMNA
SCHEMBL16271241 0.80 AR (1.00) KDM4EKMT2AMAPTHTTLMNA
SCHEMBL1669475 0.80 MAPT (0.61) KMT2AMAPTHTTLMNAKLF5
SCHEMBL1669479 0.80 MAPT (0.61) KMT2AMAPTHTTLMNAKLF5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120010075-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-01-12 US disclosed
US-20120010075-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120010075-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER SOD1, CYP51A1, SOD3 KDM4E 1473/4885KMT2A 1362/4885MAPT 1491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.