SCHEMBL6845389

SCHEMBL6845389

CC(CC(CCC(=O)Cl)C(=O)Cl)C(=O)Cl

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
ALDH1A1 P00352 2/20 0.33
TP53 P04637 1/20 0.33
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9888612 0.98 TSHR (0.34) TSHRALDH1A1TP53CYP1A2
SCHEMBL1518175 0.80 TSHR (0.43) TSHRALDH1A1TP53CYP1A2
SCHEMBL8030278 0.79 TSHR (0.41) TSHRALDH1A1TP53
SCHEMBL8841262 0.78 TSHR (0.36) TSHRALDH1A1TP53
SCHEMBL29269904 0.76 ALDH1A1 (0.52) TSHRALDH1A1TP53
SCHEMBL98864 0.76 TSHR (0.46) TSHRALDH1A1TP53
SCHEMBL20887449 0.76 SLC1A3 (0.35) TSHRCYP1A2
Hydrochloric Acid SCHEMBL7722330 0.74 TSHR (0.44) TSHRALDH1A1TP53
SCHEMBL12661385 0.74 SLC1A3 (0.34) TSHR
SCHEMBL10460142 0.74 TSHR (0.50) TSHRALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110201563-A A kind of preparation method of chlorine-resistant anti-pollution polyamide reverse osmose membrane 武汉纳霏膜科技有限公司 2019-09-06 CN claimed
CN-110201563-A A kind of preparation method of chlorine-resistant anti-pollution polyamide reverse osmose membrane 武汉纳霏膜科技有限公司 2019-09-06 CN disclosed
US-6770418-B2 ACID-CATALYZED POSITIVE RESIST COMPOSITIONS SUITABLE FOR BILAYER OR MULTILAYER LITHOGRAPHIC APPLICATIONS ARE ENABLED BY THE USE OF A COMBINATION OF (A) AN ACID-SENSITIVE IMAGING POLYMER, (B) A RADIATION SENSITIVE ACID GENERATOR, AND (C) A INTERNATIONAL BUSINESS MACHINES CORPORATION 2004-08-03 US disclosed
US-20030124453-A1 Positive resist compositions containing non-polymeric silicon aditives INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2003-07-03 US disclosed
US-6444091-B1 MIXING PULPS WITH POLYAMIDES OR IN COMBINATION WITH COAGULANTS, FLOCCULANTS AND/OR PARTICLES; EFFICIENCY NALCO CHEMICAL COMPANY 2002-09-03 US disclosed
WO-2002052102-A2 STRUCTURALLY RIGID NONIONIC AND ANIONIC POLYMERS AS RETENTION AND DRAINAGE AIDS IN PAPERMAKING ONDEO NALCO COMPANY (US) 2002-07-04 WO disclosed