SCHEMBL8030278

SCHEMBL8030278

O=C(Cl)CCC(CCC(=O)Cl)C(=O)Cl

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
ALDH1A1 P00352 2/20 0.38
TP53 P04637 1/20 0.38
FOLH1 Q04609 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10460142 0.88 TSHR (0.50) TSHRALDH1A1TP53
SCHEMBL8841262 0.87 TSHR (0.36) TSHRALDH1A1TP53FOLH1
SCHEMBL98864 0.85 TSHR (0.46) TSHRALDH1A1TP53
SCHEMBL11531366 0.84 ALDH1A1 (0.54) TSHRALDH1A1TP53
Hydrochloric Acid SCHEMBL7722330 0.83 TSHR (0.44) TSHRALDH1A1TP53
SCHEMBL11528374 0.81 ALDH1A1 (0.57) TSHRALDH1A1TP53
SCHEMBL6845389 0.79 TSHR (0.36) TSHRALDH1A1TP53
SCHEMBL9888612 0.78 TSHR (0.34) TSHRALDH1A1TP53
SCHEMBL3271707 0.77 TSHR (0.41) TSHRALDH1A1TP53FOLH1
SCHEMBL29269904 0.76 ALDH1A1 (0.52) TSHRALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9890351-B2 Encapsulates THE PROCTER & GAMBLE COMPANY (US) 2018-02-13 US disclosed
EP-2741731-B1 ENCAPSULATES PROCTER & GAMBLE (US) 2017-05-17 EP disclosed
EP-2741731-A1 ENCAPSULATES The Procter and Gamble Company (US) 2014-06-18 EP disclosed
US-20130039962-A1 ENCAPSULATES ENCAPSYS, LLC 2013-02-14 US disclosed
WO-2013022949-A1 ENCAPSULATES THE PROCTER & GAMBLE COMPANY (US) 2013-02-14 WO disclosed
US-6075131-A UTILITY AS DYES FOR INK-JET PRINTING; MONOAZO DYE CONTAINING INDANYL GROUP AND ATLEAST ONE SULFONIC ACID, HYDROXY AND AMIDE OR SULFONAMIDE GROUP ATTACHED TO NAPHTHALENE RING ZENECA LIMITED (GB) 2000-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130039962-A1 ENCAPSULATES ABCB4, PPIB, FLNB TSHR 4882/4885ALDH1A1 696/4885TP53 45/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.