SCHEMBL6845429

SCHEMBL6845429

C=CC(=O)OC(C)(C)C.Oc1ccc(C=CC=Cc2cccc(O)c2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCNB2 O95067 1/20 0.47
CDK1 P06493 1/20 0.47
CDK4 P11802 1/20 0.47
CCNB1 P14635 1/20 0.47
CCND1 P24385 1/20 0.47
CCNB3 Q8WWL7 1/20 0.47
TTR P02766 1/20 0.43
MMP1 P03956 2/20 0.42
MMP2 P08253 2/20 0.42
MMP9 P14780 2/20 0.42
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA7 P43166 2/20 0.41
CA9 Q16790 2/20 0.41
CA14 Q9ULX7 2/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
APP P05067 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2708958 0.94 CCNB2 (0.48) CCNB2CDK1CDK4CCNB1CCND1
SCHEMBL5442451 0.93 MMP1 (0.43) CCNB2CDK1CDK4CCNB1CCND1
SCHEMBL1506719 0.91 APP (0.43) TTRCA12CA1CA7CA9
SCHEMBL5440924 0.85 MAPT (0.46) MMP1MMP2MMP9CA12CA1
SCHEMBL5452249 0.84 CYP1A2 (0.45) CA12CA1CA7CA9CA14
SCHEMBL7732137 0.84 AKR1B10 (0.43) MMP1MMP2MMP9CA12CA1
SCHEMBL5438748 0.82 CA12 (0.43) CA12CA1CA7CA9CA14
SCHEMBL5432692 0.82 CA12 (0.43) MMP2MMP9CA12CA1CA7
SCHEMBL7139686 0.81 APP (0.41) TTRCA12CA1CA7CA9
SCHEMBL5440747 0.80 THRB (0.50) CA12CA1CA7CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6770413-B1 Hydroxyphenyl copolymers and photoresists comprising same SHIPLEY COMPANY, L.L.C. 2004-08-03 US disclosed
EP-1020768-A1 Hydroxystyrene copolymers and photoresists comprising same Shipley Company LLC (US) 2000-07-19 EP disclosed