Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6845531 | 0.79 | BACE1 (0.33) | BACE1CTSD | |
| SCHEMBL6845659 | 0.76 | BACE1 (0.53) | BACE1CTSD | |
| SCHEMBL16229143 | 0.67 | BACE1 (0.90) | BACE1CTSD | |
| SCHEMBL10285710 | 0.67 | BACE1 (0.51) | BACE1CTSD | |
| SCHEMBL12212608 | 0.66 | BACE1 (0.68) | BACE1CTSD | |
| SCHEMBL2372290 | 0.63 | BACE1 (1.00) | BACE1CTSD | |
| SCHEMBL2383552 | 0.63 | BACE1 (1.00) | BACE1CTSD | |
| SCHEMBL2380284 | 0.62 | BACE1 (0.76) | BACE1CTSD | |
| SCHEMBL2520572 | 0.62 | BACE1 (0.76) | BACE1CTSD | |
| SCHEMBL10285405 | 0.61 | BACE1 (0.42) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011115938-A1 | SPIRO-TETRACYCLIC RING COMPOUNDS AS BETA - SECRETASE MODULATORS | AMGEN INC. (US) | 2011-09-22 | — | — | WO | disclosed |