Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.51 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.51 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | S100A4 | P26447 | 5/20 | 0.45 |
| ▸ | NQO1 | P15559 | 3/20 | 0.44 |
| ▸ | TDP2 | O95551 | 5/20 | 0.41 |
| ▸ | NSD2 | O96028 | 4/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6841492 | 0.87 | KMT2A (0.53) | KMT2AMEN1MAPTGUCY1B2ALDH1A1 | |
| SCHEMBL6841545 | 0.87 | KMT2A (0.53) | KMT2AMEN1MAPTGUCY1B2ALDH1A1 | |
| SCHEMBL6841572 | 0.84 | KMT2A (0.50) | KMT2AMEN1MAPTGUCY1B2ALDH1A1 | |
| SCHEMBL6846912 | 0.79 | KMT2A (0.53) | KMT2AMEN1MAPTGUCY1B2ALDH1A1 | |
| SCHEMBL7721584 | 0.74 | S100A4 (0.41) | KMT2AMEN1MAPTGUCY1B2ALDH1A1 | |
| SCHEMBL29401747 | 0.69 | MAPT (1.00) | KMT2AMEN1MAPTGUCY1B2ALDH1A1 | |
| SCHEMBL970943 | 0.69 | MAPT (1.00) | KMT2AMEN1MAPTGUCY1B2ALDH1A1 | |
| SCHEMBL6845721 | 0.68 | STAT3 (0.43) | KMT2AMEN1MAPTGUCY1B2ALDH1A1 | |
| SCHEMBL7721587 | 0.68 | S100A4 (0.50) | KMT2AMEN1MAPTGUCY1B2ALDH1A1 | |
| SCHEMBL6350632 | 0.68 | MAPT (0.59) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202992-B1 | ASCIDIDEMIN DERIVATIVES AND THEIR THERAPEUTIC APPLICATIONS | CEPHALON FRANCE (FR) | 2004-09-15 | — | — | EP | disclosed |
| EP-1202992-A2 | ASCIDIDEMIN DERIVATIVES AND THEIR THERAPEUTIC APPLICATIONS | LABORATOIRE L. LAFON (FR) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001012631-A2 | ASCIDIDEMIN DERIVATIVES AND THEIR THERAPEUTIC APPLICATIONS | LABORATOIRE L. LAFON (FR) | 2001-02-22 | — | — | WO | disclosed |